rs2691678

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0193 (5782/29944,GnomAD)
G=0161 (4695/29118,TOPMED)
G=0134 (671/5008,1000G)
G=0243 (938/3854,ALSPAC)
G=0246 (911/3708,TWINSUK)
chr3:41188832 (GRCh38.p7) (3p22.1)
AD
GWASdb2
2   publication(s)
See rs on genome
166 Enhancers around
48 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.41188832A>G
GRCh37.p13 chr 3NC_000003.11:g.41230323A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.991G=0.009
1000GenomesAmericanSub694A=0.820G=0.180
1000GenomesEast AsianSub1008A=0.974G=0.026
1000GenomesEuropeSub1006A=0.727G=0.273
1000GenomesGlobalStudy-wide5008A=0.866G=0.134
1000GenomesSouth AsianSub978A=0.760G=0.240
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.757G=0.243
The Genome Aggregation DatabaseAfricanSub8726A=0.953G=0.047
The Genome Aggregation DatabaseAmericanSub832A=0.840G=0.160
The Genome Aggregation DatabaseEast AsianSub1618A=0.985G=0.015
The Genome Aggregation DatabaseEuropeSub18466A=0.722G=0.277
The Genome Aggregation DatabaseGlobalStudy-wide29944A=0.806G=0.193
The Genome Aggregation DatabaseOtherSub302A=0.660G=0.340
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.838G=0.161
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.754G=0.246
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res
23777469Haplotype association analysis of genes within the WNT signalling pathways in diabetic nephropathy.Kavanagh DHBMC Nephrol

P-Value

SNP ID p-value Traits Study
rs26916780.000277alcohol dependence20201924

eQTL of rs2691678 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2691678 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr34124541341245465E06715090
chr34124558541245645E06715262
chr34124587841246111E06715555
chr34124723241247333E06716909
chr34124801141248182E06717688
chr34124825441248337E06717931
chr34124837341248471E06718050
chr34124869841249085E06718375
chr34124917441249267E06718851
chr34124972541249775E06719402
chr34124990541250331E06719582
chr34125042741250654E06720104
chr34126096641261230E06730643
chr34127630741277084E06745984
chr34127778341277911E06747460
chr34118303741183212E068-47111
chr34118336741183665E068-46658
chr34124541341245465E06815090
chr34124558541245645E06815262
chr34124587841246111E06815555
chr34124723241247333E06816909
chr34124735141247408E06817028
chr34124801141248182E06817688
chr34124825441248337E06817931
chr34124837341248471E06818050
chr34124869841249085E06818375
chr34124917441249267E06818851
chr34124972541249775E06819402
chr34124990541250331E06819582
chr34125433141254412E06824008
chr34125458641254658E06824263
chr34125469941254836E06824376
chr34125497041255051E06824647
chr34125518141255297E06824858
chr34125563741255737E06825314
chr34125632841256430E06826005
chr34126251541262806E06832192
chr34126285741263152E06832534
chr34126357241263756E06833249
chr34126376941263836E06833446
chr34126406241264314E06833739
chr34126566141265939E06835338
chr34127630741277084E06845984
chr34118303741183212E069-47111
chr34118336741183665E069-46658
chr34124801141248182E06917688
chr34124825441248337E06917931
chr34124837341248471E06918050
chr34124869841249085E06918375
chr34124917441249267E06918851
chr34124972541249775E06919402
chr34125458641254658E06924263
chr34125469941254836E06924376
chr34125497041255051E06924647
chr34125518141255297E06924858
chr34125745741257533E06927134
chr34126357241263756E06933249
chr34126376941263836E06933446
chr34126531641265430E06934993
chr34126566141265939E06935338
chr34126598941266114E06935666
chr34127617141276268E06945848
chr34127630741277084E06945984
chr34123763141237793E0707308
chr34123779841238317E0707475
chr34124473941244876E07014416
chr34124587841246111E07015555
chr34124723241247333E07016909
chr34124735141247408E07017028
chr34124801141248182E07017688
chr34124825441248337E07017931
chr34124837341248471E07018050
chr34124869841249085E07018375
chr34124917441249267E07018851
chr34125458641254658E07024263
chr34125469941254836E07024376
chr34125497041255051E07024647
chr34125518141255297E07024858
chr34118303741183212E071-47111
chr34118336741183665E071-46658
chr34124473941244876E07114416
chr34124801141248182E07117688
chr34124825441248337E07117931
chr34124837341248471E07118050
chr34124869841249085E07118375
chr34124917441249267E07118851
chr34124972541249775E07119402
chr34124990541250331E07119582
chr34125042741250654E07120104
chr34125078041251101E07120457
chr34125113341251199E07120810
chr34125469941254836E07124376
chr34125497041255051E07124647
chr34125518141255297E07124858
chr34125632841256430E07126005
chr34126357241263756E07133249
chr34126376941263836E07133446
chr34126406241264314E07133739
chr34127127641271431E07140953
chr34127630741277084E07145984
chr34127778341277911E07147460
chr34124473941244876E07214416
chr34124541341245465E07215090
chr34124558541245645E07215262
chr34124990541250331E07219582
chr34125042741250654E07220104
chr34126251541262806E07232192
chr34126285741263152E07232534
chr34126357241263756E07233249
chr34126376941263836E07233446
chr34126406241264314E07233739
chr34127617141276268E07245848
chr34127630741277084E07245984
chr34124801141248182E07317688
chr34124825441248337E07317931
chr34124837341248471E07318050
chr34124869841249085E07318375
chr34124917441249267E07318851
chr34126598941266114E07335666
chr34127630741277084E07345984
chr34127778341277911E07347460
chr34118303741183212E074-47111
chr34124473941244876E07414416
chr34124541341245465E07415090
chr34124558541245645E07415262
chr34124587841246111E07415555
chr34124723241247333E07416909
chr34124735141247408E07417028
chr34124801141248182E07417688
chr34124825441248337E07417931
chr34124837341248471E07418050
chr34124869841249085E07418375
chr34124917441249267E07418851
chr34124972541249775E07419402
chr34124990541250331E07419582
chr34125042741250654E07420104
chr34125850241258769E07428179
chr34126251541262806E07432192
chr34126285741263152E07432534
chr34126357241263756E07433249
chr34126376941263836E07433446
chr34126566141265939E07435338
chr34127617141276268E07445848
chr34127630741277084E07445984
chr34127778341277911E07447460
chr34124735141247408E08117028
chr34124801141248182E08117688
chr34126077841260836E08130455
chr34126096641261230E08130643
chr34126251541262806E08132192
chr34126285741263152E08132534
chr34127617141276268E08145848
chr34127630741277084E08145984
chr34124473941244876E08214416
chr34124541341245465E08215090
chr34124558541245645E08215262
chr34124587841246111E08215555
chr34124723241247333E08216909
chr34124735141247408E08217028
chr34124837341248471E08218050
chr34124869841249085E08218375
chr34124917441249267E08218851
chr34126096641261230E08230643
chr34126251541262806E08232192
chr34127617141276268E08245848
chr34127630741277084E08245984










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr34123997141242697E0679648
chr34124286841242951E06712545
chr34124295541243119E06712632
chr34124316441243214E06712841
chr34124327941243329E06712956
chr34124347041243549E06713147
chr34123997141242697E0689648
chr34124286841242951E06812545
chr34124295541243119E06812632
chr34124316441243214E06812841
chr34124327941243329E06812956
chr34123997141242697E0699648
chr34124286841242951E06912545
chr34124295541243119E06912632
chr34124316441243214E06912841
chr34123997141242697E0709648
chr34124286841242951E07012545
chr34124295541243119E07012632
chr34124316441243214E07012841
chr34124327941243329E07012956
chr34124347041243549E07013147
chr34123997141242697E0719648
chr34124347041243549E07113147
chr34123997141242697E0729648
chr34124286841242951E07212545
chr34124295541243119E07212632
chr34124316441243214E07212841
chr34124327941243329E07212956
chr34124347041243549E07213147
chr34123997141242697E0739648
chr34124286841242951E07312545
chr34124295541243119E07312632
chr34124316441243214E07312841
chr34124327941243329E07312956
chr34124347041243549E07313147
chr34123997141242697E0749648
chr34123997141242697E0819648
chr34124286841242951E08112545
chr34124295541243119E08112632
chr34124316441243214E08112841
chr34124327941243329E08112956
chr34124347041243549E08113147
chr34123997141242697E0829648
chr34124286841242951E08212545
chr34124295541243119E08212632
chr34124316441243214E08212841
chr34124327941243329E08212956
chr34124347041243549E08213147