rs2700586

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0358 (10686/29826,GnomAD)
T=0394 (11493/29118,TOPMED)
T=0396 (1984/5008,1000G)
T=0276 (1063/3854,ALSPAC)
T=0276 (1025/3708,TWINSUK)
chr3:99375946 (GRCh38.p7) (3q12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.99375946C>T
GRCh37.p13 chr 3NC_000003.11:g.99094790C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.380T=0.620
1000GenomesAmericanSub694C=0.680T=0.320
1000GenomesEast AsianSub1008C=0.672T=0.328
1000GenomesEuropeSub1006C=0.759T=0.241
1000GenomesGlobalStudy-wide5008C=0.604T=0.396
1000GenomesSouth AsianSub978C=0.620T=0.380
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.724T=0.276
The Genome Aggregation DatabaseAfricanSub8674C=0.421T=0.579
The Genome Aggregation DatabaseAmericanSub830C=0.720T=0.280
The Genome Aggregation DatabaseEast AsianSub1594C=0.696T=0.304
The Genome Aggregation DatabaseEuropeSub18426C=0.733T=0.266
The Genome Aggregation DatabaseGlobalStudy-wide29826C=0.641T=0.358
The Genome Aggregation DatabaseOtherSub302C=0.910T=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.605T=0.394
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.724T=0.276
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs27005860.00035alcohol dependence20201924

eQTL of rs2700586 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2700586 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.