rs27006

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0287 (8597/29902,GnomAD)
A=0235 (6859/29118,TOPMED)
A=0298 (1490/5008,1000G)
A=0283 (1091/3854,ALSPAC)
A=0269 (996/3708,TWINSUK)
chr5:56271754 (GRCh38.p7) (5q11.2)
AD
GWASdb2
1   publication(s)
See rs on genome
13 Enhancers around
13 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.56271754G>A
GRCh37.p13 chr 5NC_000005.9:g.55567581G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.803A=0.197
1000GenomesAmericanSub694G=0.720A=0.280
1000GenomesEast AsianSub1008G=0.615A=0.385
1000GenomesEuropeSub1006G=0.712A=0.288
1000GenomesGlobalStudy-wide5008G=0.702A=0.298
1000GenomesSouth AsianSub978G=0.630A=0.370
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.717A=0.283
The Genome Aggregation DatabaseAfricanSub8714G=0.803A=0.197
The Genome Aggregation DatabaseAmericanSub838G=0.690A=0.310
The Genome Aggregation DatabaseEast AsianSub1614G=0.616A=0.384
The Genome Aggregation DatabaseEuropeSub18434G=0.679A=0.320
The Genome Aggregation DatabaseGlobalStudy-wide29902G=0.712A=0.287
The Genome Aggregation DatabaseOtherSub302G=0.710A=0.290
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.764A=0.235
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.731A=0.269
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs270060.00014alcohol dependence20201924

eQTL of rs27006 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs27006 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr55556622055567219E068-362
chr55557581655576124E0708235
chr55559522955595428E07027648
chr55556622055567219E071-362
chr55556946255569682E0741881
chr55552732955527485E081-40096
chr55552761455527654E081-39927
chr55554131155541651E081-25930
chr55557869255578742E08111111
chr55559436555594456E08126784
chr55559452455594864E08126943
chr55559497155595164E08127390
chr55559522955595428E08127648





Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr55552853755528611E067-38970
chr55552870255528862E067-38719
chr55552853755528611E068-38970
chr55552870255528862E068-38719
chr55552853755528611E069-38970
chr55552870255528862E069-38719
chr55552870255528862E071-38719
chr55552853755528611E072-38970
chr55552870255528862E072-38719
chr55552853755528611E073-38970
chr55552870255528862E073-38719
chr55552853755528611E081-38970
chr55552870255528862E081-38719