rs2700667

Homo sapiens
G>A / G>C
None
Check p-value
SNV (Single Nucleotide Variation)
A=0359 (10714/29832,GnomAD)
A=0394 (11491/29118,TOPMED)
A=0396 (1984/5008,1000G)
A=0276 (1063/3854,ALSPAC)
A=0277 (1026/3708,TWINSUK)
chr3:99366962 (GRCh38.p7) (3q12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
24 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.99366962G>A
GRCh38.p7 chr 3NC_000003.12:g.99366962G>C
GRCh37.p13 chr 3NC_000003.11:g.99085806G>A
GRCh37.p13 chr 3NC_000003.11:g.99085806G>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.380A=0.620
1000GenomesAmericanSub694G=0.680A=0.320
1000GenomesEast AsianSub1008G=0.674A=0.326
1000GenomesEuropeSub1006G=0.759A=0.241
1000GenomesGlobalStudy-wide5008G=0.604A=0.396
1000GenomesSouth AsianSub978G=0.620A=0.380
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.724A=0.276
The Genome Aggregation DatabaseAfricanSub8694G=0.421C=0.000
The Genome Aggregation DatabaseAmericanSub836G=0.710C=0.00,
The Genome Aggregation DatabaseEast AsianSub1570G=0.699C=0.000
The Genome Aggregation DatabaseEuropeSub18430G=0.732C=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29832G=0.640C=0.000
The Genome Aggregation DatabaseOtherSub302G=0.910C=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.605A=0.394
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.723A=0.277
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs27006670.0004alcohol dependence20201924

eQTL of rs2700667 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2700667 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3111392465111392575E067-1047
chr3111392465111392575E068-1047
chr3111371458111371601E070-22021
chr3111396438111396531E0702816
chr3111396968111397100E0703346
chr3111430996111431100E07037374
chr3111431154111431952E07037532
chr3111392389111392461E071-1161
chr3111392465111392575E071-1047
chr3111392212111392279E072-1343
chr3111392389111392461E072-1161
chr3111392465111392575E072-1047
chr3111392389111392461E073-1161
chr3111392465111392575E073-1047
chr3111354968111355164E081-38458
chr3111355271111355340E081-38282
chr3111355344111355634E081-37988
chr3111392389111392461E081-1161
chr3111392465111392575E081-1047
chr3111396438111396531E0812816
chr3111396968111397100E0813346
chr3111430996111431100E08137374
chr3111431154111431952E08137532
chr3111431154111431952E08237532








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3111392756111394642E0670
chr3111392756111394642E0680
chr3111392756111394642E0690
chr3111392756111394642E0700
chr3111392756111394642E0710
chr3111392756111394642E0720
chr3111392756111394642E0730
chr3111392756111394642E0740
chr3111392756111394642E0810
chr3111392756111394642E0820