rs2708914

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
T==0428 (12824/29922,GnomAD)
T==0468 (13627/29116,TOPMED)
G=0475 (2377/5008,1000G)
T==0317 (1221/3854,ALSPAC)
T==0328 (1218/3708,TWINSUK)
chr2:112869657 (GRCh38.p7) (2q14.1)
AD
GWASdb2
1   publication(s)
See rs on genome
68 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.112869657T>G
GRCh37.p13 chr 2NC_000002.11:g.113627234T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.630G=0.370
1000GenomesAmericanSub694T=0.550G=0.450
1000GenomesEast AsianSub1008T=0.484G=0.516
1000GenomesEuropeSub1006T=0.338G=0.662
1000GenomesGlobalStudy-wide5008T=0.525G=0.475
1000GenomesSouth AsianSub978T=0.600G=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.317G=0.683
The Genome Aggregation DatabaseAfricanSub8710T=0.601G=0.399
The Genome Aggregation DatabaseAmericanSub838T=0.550G=0.450
The Genome Aggregation DatabaseEast AsianSub1620T=0.459G=0.541
The Genome Aggregation DatabaseEuropeSub18456T=0.340G=0.659
The Genome Aggregation DatabaseGlobalStudy-wide29922T=0.428G=0.571
The Genome Aggregation DatabaseOtherSub298T=0.320G=0.680
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.468G=0.532
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.328G=0.672
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs27089140.000447alcohol dependence20201924

eQTL of rs2708914 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2708914 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2113627573113627734E067339
chr2113628266113628332E0671032
chr2113628413113628487E0671179
chr2113628529113628740E0671295
chr2113628899113629083E0671665
chr2113638179113638285E06710945
chr2113638319113639332E06711085
chr2113639552113639674E06712318
chr2113581903113582195E068-45039
chr2113582279113582799E068-44435
chr2113628266113628332E0681032
chr2113628413113628487E0681179
chr2113628529113628740E0681295
chr2113628899113629083E0681665
chr2113637561113638015E06810327
chr2113638179113638285E06810945
chr2113638319113639332E06811085
chr2113639552113639674E06812318
chr2113627573113627734E069339
chr2113628266113628332E0691032
chr2113628413113628487E0691179
chr2113628529113628740E0691295
chr2113628899113629083E0691665
chr2113629167113629307E0691933
chr2113637561113638015E06910327
chr2113638179113638285E06910945
chr2113638319113639332E06911085
chr2113639552113639674E06912318
chr2113627573113627734E070339
chr2113628413113628487E0701179
chr2113628529113628740E0701295
chr2113667975113668032E07040741
chr2113581903113582195E071-45039
chr2113592037113592255E071-34979
chr2113626743113627544E0710
chr2113627573113627734E071339
chr2113628266113628332E0711032
chr2113628413113628487E0711179
chr2113628529113628740E0711295
chr2113628899113629083E0711665
chr2113637145113637296E0719911
chr2113637561113638015E07110327
chr2113638179113638285E07110945
chr2113638319113639332E07111085
chr2113639552113639674E07112318
chr2113626743113627544E0720
chr2113627573113627734E072339
chr2113628266113628332E0721032
chr2113638179113638285E07210945
chr2113638319113639332E07211085
chr2113639552113639674E07212318
chr2113647758113647880E07220524
chr2113628529113628740E0731295
chr2113628899113629083E0731665
chr2113629167113629307E0731933
chr2113637561113638015E07310327
chr2113638179113638285E07310945
chr2113638319113639332E07311085
chr2113626743113627544E0740
chr2113627573113627734E074339
chr2113628266113628332E0741032
chr2113628413113628487E0741179
chr2113628529113628740E0741295
chr2113628899113629083E0741665
chr2113629167113629307E0741933
chr2113638179113638285E07410945
chr2113638319113639332E07411085
chr2113639552113639674E07412318