rs2724432

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0214 (6441/29980,GnomAD)
T=0224 (6549/29118,TOPMED)
T=0150 (752/5008,1000G)
T=0223 (858/3854,ALSPAC)
T=0217 (804/3708,TWINSUK)
chr11:110413469 (GRCh38.p7) (11q22.3)
ND
GWASdb2
2   publication(s)
See rs on genome
64 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.110413469C>T
GRCh37.p13 chr 11NC_000011.9:g.110284193C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.747T=0.253
1000GenomesAmericanSub694C=0.870T=0.130
1000GenomesEast AsianSub1008C=0.959T=0.041
1000GenomesEuropeSub1006C=0.780T=0.220
1000GenomesGlobalStudy-wide5008C=0.850T=0.150
1000GenomesSouth AsianSub978C=0.930T=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.777T=0.223
The Genome Aggregation DatabaseAfricanSub8722C=0.742T=0.258
The Genome Aggregation DatabaseAmericanSub836C=0.880T=0.120
The Genome Aggregation DatabaseEast AsianSub1622C=0.959T=0.041
The Genome Aggregation DatabaseEuropeSub18498C=0.786T=0.213
The Genome Aggregation DatabaseGlobalStudy-wide29980C=0.785T=0.214
The Genome Aggregation DatabaseOtherSub302C=0.770T=0.230
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.775T=0.224
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.783T=0.217
PMID Title Author Journal
24987808Variants identified by hepatocellular carcinoma and chronic hepatitis B virus infection susceptibility GWAS associated with survival in HBV-related hepatocellular carcinoma.Li CPLoS One
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs27244320.00045nicotine dependence17158188

eQTL of rs2724432 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2724432 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11110234355110234584E067-49609
chr11110247286110248056E067-36137
chr11110330076110330206E06745883
chr11110330210110330321E06746017
chr11110330341110330416E06746148
chr11110330433110330506E06746240
chr11110330958110331035E06746765
chr11110331041110331143E06746848
chr11110236923110237497E068-46696
chr11110243695110244609E068-39584
chr11110303112110305027E06818919
chr11110330076110330206E06845883
chr11110330210110330321E06846017
chr11110330341110330416E06846148
chr11110330433110330506E06846240
chr11110234355110234584E069-49609
chr11110247193110247249E069-36944
chr11110247286110248056E069-36137
chr11110318237110318916E06934044
chr11110319215110319313E06935022
chr11110330076110330206E06945883
chr11110330210110330321E06946017
chr11110330341110330416E06946148
chr11110330433110330506E06946240
chr11110330958110331035E06946765
chr11110331041110331143E06946848
chr11110331250110331566E06947057
chr11110243695110244609E070-39584
chr11110234355110234584E071-49609
chr11110303112110305027E07118919
chr11110319377110319638E07135184
chr11110330076110330206E07145883
chr11110330210110330321E07146017
chr11110330341110330416E07146148
chr11110330433110330506E07146240
chr11110330958110331035E07146765
chr11110331041110331143E07146848
chr11110234355110234584E072-49609
chr11110247286110248056E072-36137
chr11110319215110319313E07235022
chr11110330341110330416E07246148
chr11110330433110330506E07246240
chr11110330958110331035E07246765
chr11110331041110331143E07246848
chr11110234355110234584E073-49609
chr11110330076110330206E07345883
chr11110330210110330321E07346017
chr11110330341110330416E07346148
chr11110330433110330506E07346240
chr11110330958110331035E07346765
chr11110331041110331143E07346848
chr11110331250110331566E07347057
chr11110247193110247249E074-36944
chr11110247286110248056E074-36137
chr11110303112110305027E07418919
chr11110319215110319313E07435022
chr11110319377110319638E07435184
chr11110330076110330206E07445883
chr11110330210110330321E07446017
chr11110330341110330416E07446148
chr11110330433110330506E07446240
chr11110330958110331035E07446765
chr11110331041110331143E07446848
chr11110331250110331566E07447057








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr11110299784110303022E06715591
chr11110299784110303022E06815591
chr11110299784110303022E06915591
chr11110299784110303022E07015591
chr11110299784110303022E07115591
chr11110299784110303022E07215591
chr11110299784110303022E07315591
chr11110299784110303022E07415591
chr11110299784110303022E08115591
chr11110299784110303022E08215591