rs2733020

Homo sapiens
A>C / A>T
None
Check p-value
SNV (Single Nucleotide Variation)
C=0102 (3067/29968,GnomAD)
C=0117 (3414/29118,TOPMED)
C=0069 (348/5008,1000G)
C=0089 (344/3854,ALSPAC)
C=0094 (348/3708,TWINSUK)
chr8:5724168 (GRCh38.p7) (8p23.2)
AD
GWASdb2
1   publication(s)
See rs on genome
13 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.5724168A>C
GRCh38.p7 chr 8NC_000008.11:g.5724168A>T
GRCh37.p13 chr 8NC_000008.10:g.5581690A>C
GRCh37.p13 chr 8NC_000008.10:g.5581690A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.829C=0.171
1000GenomesAmericanSub694A=0.950C=0.050
1000GenomesEast AsianSub1008A=1.000C=0.000
1000GenomesEuropeSub1006A=0.928C=0.072
1000GenomesGlobalStudy-wide5008A=0.931C=0.069
1000GenomesSouth AsianSub978A=0.980C=0.020
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.911C=0.089
The Genome Aggregation DatabaseAfricanSub8724A=0.843C=0.157
The Genome Aggregation DatabaseAmericanSub838A=0.940C=0.060
The Genome Aggregation DatabaseEast AsianSub1622A=0.999C=0.001
The Genome Aggregation DatabaseEuropeSub18482A=0.912C=0.087
The Genome Aggregation DatabaseGlobalStudy-wide29968A=0.897C=0.102
The Genome Aggregation DatabaseOtherSub302A=0.920C=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.882C=0.117
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.906C=0.094
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs27330200.00023alcohol dependence20201924

eQTL of rs2733020 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2733020 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr82437776624377873E07130663
chr82437808924378144E07130986
chr82436899624369082E07421893
chr82437776624377873E07430663
chr82437808924378144E07430986
chr82439213024392367E08145027
chr82439293624393405E08145833
chr82436591124366391E08218808
chr82436650124366572E08219398
chr82436662524367359E08219522
chr82436736824367467E08220265
chr82436768524367818E08220582
chr82436794324368019E08220840