rs2733022

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0100 (3007/29898,GnomAD)
C=0115 (3376/29118,TOPMED)
C=0069 (346/5008,1000G)
C=0088 (341/3854,ALSPAC)
C=0094 (347/3708,TWINSUK)
chr8:5724652 (GRCh38.p7) (8p23.2)
AD
GWASdb2
1   publication(s)
See rs on genome
8 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.5724652T>C
GRCh37.p13 chr 8NC_000008.10:g.5582174T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.831C=0.169
1000GenomesAmericanSub694T=0.950C=0.050
1000GenomesEast AsianSub1008T=1.000C=0.000
1000GenomesEuropeSub1006T=0.928C=0.072
1000GenomesGlobalStudy-wide5008T=0.931C=0.069
1000GenomesSouth AsianSub978T=0.980C=0.020
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.912C=0.088
The Genome Aggregation DatabaseAfricanSub8690T=0.846C=0.154
The Genome Aggregation DatabaseAmericanSub836T=0.940C=0.060
The Genome Aggregation DatabaseEast AsianSub1622T=0.999C=0.001
The Genome Aggregation DatabaseEuropeSub18448T=0.913C=0.086
The Genome Aggregation DatabaseGlobalStudy-wide29898T=0.899C=0.100
The Genome Aggregation DatabaseOtherSub302T=0.920C=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.884C=0.115
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.906C=0.094
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs27330220.00026alcohol dependence20201924

eQTL of rs2733022 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2733022 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr855338925534065E081-48109
chr855342775534401E081-47773
chr855344105534570E081-47604
chr855345745534624E081-47550
chr855346725534726E081-47448
chr856164965616701E08134322
chr856168375616898E08134663
chr856170585617108E08134884