SNP Detail Info-rs2733022

Organism: Homo sapiens

Alleles: T>C

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C=0100 (3007/29898,GnomAD)
C=0115 (3376/29118,TOPMED)
C=0069 (346/5008,1000G)
C=0088 (341/3854,ALSPAC)
C=0094 (347/3708,TWINSUK)

Position: chr8:5724652 (GRCh38.p7) (8p23.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 8 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 8	NC_000008.11:g.5724652T>C
GRCh37.p13 chr 8	NC_000008.10:g.5582174T>C

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.831	C=0.169
1000Genomes	American	Sub	694	T=0.950	C=0.050
1000Genomes	East Asian	Sub	1008	T=1.000	C=0.000
1000Genomes	Europe	Sub	1006	T=0.928	C=0.072
1000Genomes	Global	Study-wide	5008	T=0.931	C=0.069
1000Genomes	South Asian	Sub	978	T=0.980	C=0.020
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.912	C=0.088
The Genome Aggregation Database	African	Sub	8690	T=0.846	C=0.154
The Genome Aggregation Database	American	Sub	836	T=0.940	C=0.060
The Genome Aggregation Database	East Asian	Sub	1622	T=0.999	C=0.001
The Genome Aggregation Database	Europe	Sub	18448	T=0.913	C=0.086
The Genome Aggregation Database	Global	Study-wide	29898	T=0.899	C=0.100
The Genome Aggregation Database	Other	Sub	302	T=0.920	C=0.080
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.884	C=0.115
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.906	C=0.094

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs2733022	0.00026	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr8	5533892	5534065	E081	-48109
chr8	5534277	5534401	E081	-47773
chr8	5534410	5534570	E081	-47604
chr8	5534574	5534624	E081	-47550
chr8	5534672	5534726	E081	-47448
chr8	5616496	5616701	E081	34322
chr8	5616837	5616898	E081	34663
chr8	5617058	5617108	E081	34884

rs2733022