rs2746183

Homo sapiens
A>C / A>T
None
Check p-value
SNV (Single Nucleotide Variation)
A==0197 (5918/29934,GnomAD)
A==0209 (6096/29118,TOPMED)
A==0174 (871/5008,1000G)
A==0144 (555/3854,ALSPAC)
A==0150 (557/3708,TWINSUK)
chr6:41657691 (GRCh38.p7) (6p21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.41657691A>C
GRCh38.p7 chr 6NC_000006.12:g.41657691A>T
GRCh37.p13 chr 6NC_000006.11:g.41625429A>C
GRCh37.p13 chr 6NC_000006.11:g.41625429A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.325C=0.675
1000GenomesAmericanSub694A=0.090C=0.910
1000GenomesEast AsianSub1008A=0.118C=0.882
1000GenomesEuropeSub1006A=0.164C=0.836
1000GenomesGlobalStudy-wide5008A=0.174C=0.826
1000GenomesSouth AsianSub978A=0.100C=0.900
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.144C=0.856
The Genome Aggregation DatabaseAfricanSub8708A=0.295C=0.705
The Genome Aggregation DatabaseAmericanSub838A=0.080C=0.920
The Genome Aggregation DatabaseEast AsianSub1620A=0.094C=0.906
The Genome Aggregation DatabaseEuropeSub18468A=0.167C=0.832
The Genome Aggregation DatabaseGlobalStudy-wide29934A=0.197C=0.802
The Genome Aggregation DatabaseOtherSub300A=0.100C=0.900
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.209C=0.790
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.150C=0.850
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs27461830.00055alcohol dependence(early age of onset)20201924
rs27461830.00086alcohol dependence20201924

eQTL of rs2746183 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2746183 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.