rs2772354

Homo sapiens
A>G
FARP1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0155 (4653/29972,GnomAD)
A==0095 (2769/29118,TOPMED)
A==0244 (1221/5008,1000G)
A==0135 (520/3854,ALSPAC)
A==0124 (458/3708,TWINSUK)
chr13:98383634 (GRCh38.p7) (13q32.2)
AD
GWASdb2
1   publication(s)
See rs on genome
110 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.98383634A>G
GRCh37.p13 chr 13NC_000013.10:g.99035888A>G

Gene: FARP1, FERM, ARH/RhoGEF and pleckstrin domain protein 1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
FARP1 transcript variant 3NM_001286839.1:c.N/AIntron Variant
FARP1 transcript variant 1NM_005766.3:c.N/AIntron Variant
FARP1 transcript variant 2NM_001001715.3:c.N/AGenic Downstream Transcript Variant
FARP1 transcript variant X1XM_011521046.2:c.N/AIntron Variant
FARP1 transcript variant X2XM_017020312.1:c.N/AIntron Variant
FARP1 transcript variant X3XM_017020313.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.008G=0.992
1000GenomesAmericanSub694A=0.320G=0.680
1000GenomesEast AsianSub1008A=0.570G=0.430
1000GenomesEuropeSub1006A=0.130G=0.870
1000GenomesGlobalStudy-wide5008A=0.244G=0.756
1000GenomesSouth AsianSub978A=0.290G=0.710
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.135G=0.865
The Genome Aggregation DatabaseAfricanSub8734A=0.030G=0.970
The Genome Aggregation DatabaseAmericanSub836A=0.350G=0.650
The Genome Aggregation DatabaseEast AsianSub1616A=0.576G=0.424
The Genome Aggregation DatabaseEuropeSub18484A=0.169G=0.830
The Genome Aggregation DatabaseGlobalStudy-wide29972A=0.155G=0.844
The Genome Aggregation DatabaseOtherSub302A=0.100G=0.900
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.095G=0.904
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.124G=0.876
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs27723540.000975alcohol dependence20201924

eQTL of rs2772354 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2772354 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr139898782298987921E067-47967
chr139900049399001409E067-34479
chr139898630398986525E068-49363
chr139905729299057804E06821404
chr139898782298987921E069-47967
chr139898811998988251E069-47637
chr139899969998999825E069-36063
chr139900010499000339E069-35549
chr139900049399001409E069-34479
chr139900210099002532E069-33356
chr139900270499002756E069-33132
chr139904590399045957E06910015
chr139904610499046511E06910216
chr139904672699046800E06910838
chr139900010499000339E070-35549
chr139900049399001409E070-34479
chr139901637799016431E070-19457
chr139901653099016757E070-19131
chr139901699099017077E070-18811
chr139901713899017189E070-18699
chr139901721699017270E070-18618
chr139901748399017588E070-18300
chr139901763699017861E070-18027
chr139901795599018071E070-17817
chr139901817399018270E070-17618
chr139901848399018579E070-17309
chr139904917599049257E07013287
chr139904939399049467E07013505
chr139904952599049758E07013637
chr139904983599049885E07013947
chr139904994499050054E07014056
chr139905729299057804E07021404
chr139905789999057956E07022011
chr139905809499058552E07022206
chr139905860599058967E07022717
chr139905913999059189E07023251
chr139900142799001574E071-34314
chr139903778099037820E0711892
chr139903798799038130E0712099
chr139898630398986525E072-49363
chr139900010499000339E072-35549
chr139900049399001409E074-34479
chr139902077999020880E074-15008
chr139902099799021146E074-14742
chr139904558399045633E0749695
chr139904570799045747E0749819
chr139904590399045957E07410015
chr139904610499046511E07410216
chr139899529298995559E081-40329
chr139899556198995668E081-40220
chr139899589498996058E081-39830
chr139899969998999825E081-36063
chr139900010499000339E081-35549
chr139900049399001409E081-34479
chr139900142799001574E081-34314
chr139900169999001800E081-34088
chr139900199799002063E081-33825
chr139901380699013887E081-22001
chr139901397799014059E081-21829
chr139901795599018071E081-17817
chr139901817399018270E081-17618
chr139901848399018579E081-17309
chr139901875799019031E081-16857
chr139904240699042974E0816518
chr139904335699043406E0817468
chr139904983599049885E08113947
chr139905092599051129E08115037
chr139905129799051434E08115409
chr139905370999053759E08117821
chr139905380699053925E08117918
chr139905720099057250E08121312
chr139905729299057804E08121404
chr139905789999057956E08122011
chr139905809499058552E08122206
chr139905860599058967E08122717
chr139907169299071975E08135804
chr139908068899080789E08144800
chr139908079099080891E08144902
chr139908116299081216E08145274
chr139908141299081462E08145524
chr139908200099082060E08146112
chr139899969998999825E082-36063
chr139900010499000339E082-35549
chr139900049399001409E082-34479
chr139900142799001574E082-34314
chr139900210099002532E082-33356
chr139901637799016431E082-19457
chr139901653099016757E082-19131
chr139901699099017077E082-18811
chr139901713899017189E082-18699
chr139901721699017270E082-18618
chr139901748399017588E082-18300
chr139901763699017861E082-18027
chr139901795599018071E082-17817
chr139901817399018270E082-17618
chr139901848399018579E082-17309
chr139901875799019031E082-16857
chr139904240699042974E0826518
chr139904335699043406E0827468
chr139905129799051434E08215409
chr139905196499052325E08216076
chr139905240899052528E08216520
chr139905265899052712E08216770
chr139905276799052823E08216879
chr139905789999057956E08222011
chr139905809499058552E08222206
chr139905860599058967E08222717
chr139905913999059189E08223251
chr139906212199062175E08226233
chr139906251499062564E08226626