rs2778010

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0214 (6423/29940,GnomAD)
C=0240 (6999/29118,TOPMED)
C=0196 (982/5008,1000G)
C=0227 (873/3854,ALSPAC)
C=0234 (866/3708,TWINSUK)
chr1:157651723 (GRCh38.p7) (1q23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.157651723T>C
GRCh37.p13 chr 1NC_000001.10:g.157621513T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.693C=0.307
1000GenomesAmericanSub694T=0.830C=0.170
1000GenomesEast AsianSub1008T=0.897C=0.103
1000GenomesEuropeSub1006T=0.790C=0.210
1000GenomesGlobalStudy-wide5008T=0.804C=0.196
1000GenomesSouth AsianSub978T=0.850C=0.150
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.773C=0.227
The Genome Aggregation DatabaseAfricanSub8698T=0.731C=0.269
The Genome Aggregation DatabaseAmericanSub838T=0.830C=0.170
The Genome Aggregation DatabaseEast AsianSub1616T=0.893C=0.107
The Genome Aggregation DatabaseEuropeSub18486T=0.799C=0.200
The Genome Aggregation DatabaseGlobalStudy-wide29940T=0.785C=0.214
The Genome Aggregation DatabaseOtherSub302T=0.800C=0.200
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.759C=0.240
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.766C=0.234
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs27780100.000388alcohol dependence21314694

eQTL of rs2778010 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2778010 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1157659915157659965E08138402
chr1157660872157661720E08139359
chr1157661856157661951E08140343
chr1157659915157659965E08238402