rs2798253

Homo sapiens
G>C
None
Check p-value
SNV (Single Nucleotide Variation)
G==0343 (10232/29786,GnomAD)
G==0414 (2072/5008,1000G)
G==0373 (1436/3854,ALSPAC)
G==0369 (1367/3708,TWINSUK)
chr10:92443148 (GRCh38.p7) (10q23.33)
ND
GWASdb2
1   publication(s)
See rs on genome
7 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.92443148G>C
GRCh37.p13 chr 10NC_000010.10:g.94202905G>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.215C=0.785
1000GenomesAmericanSub694G=0.310C=0.690
1000GenomesEast AsianSub1008G=0.674C=0.326
1000GenomesEuropeSub1006G=0.375C=0.625
1000GenomesGlobalStudy-wide5008G=0.414C=0.586
1000GenomesSouth AsianSub978G=0.530C=0.470
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.373C=0.627
The Genome Aggregation DatabaseAfricanSub8716G=0.253C=0.747
The Genome Aggregation DatabaseAmericanSub834G=0.300C=0.700
The Genome Aggregation DatabaseEast AsianSub1608G=0.656C=0.344
The Genome Aggregation DatabaseEuropeSub18328G=0.360C=0.639
The Genome Aggregation DatabaseGlobalStudy-wide29786G=0.343C=0.656
The Genome Aggregation DatabaseOtherSub300G=0.400C=0.600
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.369C=0.631
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs27982531.93E-06alcohol and nictotine co-dependence20158304

eQTL of rs2798253 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2798253 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr109416455894164611E072-38294
chr109416490994165023E072-37882
chr109416512794165548E072-37357
chr109416455894164611E073-38294
chr109416490994165023E073-37882
chr109416680894166960E073-35945
chr109423930494239721E08136399