SNP Detail Info-rs2798983

Organism: Homo sapiens

Alleles: C>T

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C=0238 (7125/29842,GnomAD)
C=0220 (6422/29118,TOPMED)
C=0231 (1158/5008,1000G)
C=0283 (1090/3854,ALSPAC)
C=0283 (1048/3708,TWINSUK)

Position: chr14:41303030 (GRCh38.p7) (14q21.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 14	NC_000014.9:g.41303030C>T
GRCh37.p13 chr 14	NC_000014.8:g.41772233T>C

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.874	C==0.126
1000Genomes	American	Sub	694	T=0.790	C==0.210
1000Genomes	East Asian	Sub	1008	T=0.750	C==0.250
1000Genomes	Europe	Sub	1006	T=0.736	C==0.264
1000Genomes	Global	Study-wide	5008	T=0.769	C==0.231
1000Genomes	South Asian	Sub	978	T=0.670	C==0.330
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.717	C==0.283
The Genome Aggregation Database	African	Sub	8720	T=0.817	C==0.183
The Genome Aggregation Database	American	Sub	832	T=0.830	C==0.170
The Genome Aggregation Database	East Asian	Sub	1586	T=0.740	C==0.260
The Genome Aggregation Database	Europe	Sub	18402	T=0.733	C==0.266
The Genome Aggregation Database	Global	Study-wide	29842	T=0.761	C==0.238
The Genome Aggregation Database	Other	Sub	302	T=0.750	C==0.250
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.779	C==0.220
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.717	C==0.283

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs2798983	4.77E-05	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr14	41754505	41754720	E070	-17513
chr14	41747200	41747372	E081	-24861
chr14	41747200	41747372	E082	-24861

rs2798983