rs2822567

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0252 (7574/29962,GnomAD)
T=0268 (7813/29118,TOPMED)
T=0266 (1332/5008,1000G)
T=0186 (717/3854,ALSPAC)
T=0197 (731/3708,TWINSUK)
chr21:14319749 (GRCh38.p7) (21q11.2)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
7 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 21NC_000021.9:g.14319749C>T
GRCh37.p13 chr 21NC_000021.8:g.15692070C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.619T=0.381
1000GenomesAmericanSub694C=0.830T=0.170
1000GenomesEast AsianSub1008C=0.726T=0.274
1000GenomesEuropeSub1006C=0.790T=0.210
1000GenomesGlobalStudy-wide5008C=0.734T=0.266
1000GenomesSouth AsianSub978C=0.770T=0.230
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.814T=0.186
The Genome Aggregation DatabaseAfricanSub8714C=0.644T=0.356
The Genome Aggregation DatabaseAmericanSub838C=0.820T=0.180
The Genome Aggregation DatabaseEast AsianSub1620C=0.712T=0.288
The Genome Aggregation DatabaseEuropeSub18488C=0.795T=0.204
The Genome Aggregation DatabaseGlobalStudy-wide29962C=0.747T=0.252
The Genome Aggregation DatabaseOtherSub302C=0.750T=0.250
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.731T=0.268
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.803T=0.197
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs28225670.00091alcohol dependence20201924

eQTL of rs2822567 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2822567 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr211564593915646819E067-45251
chr211564593915646819E068-45251
chr211564593915646819E069-45251
chr211564593915646819E071-45251
chr211564593915646819E072-45251
chr211564593915646819E073-45251
chr211564593915646819E074-45251