rs2822582

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0478 (14311/29910,GnomAD)
T==0446 (13001/29118,TOPMED)
T==0423 (2117/5008,1000G)
G=0372 (1435/3854,ALSPAC)
G=0379 (1405/3708,TWINSUK)
chr21:14337293 (GRCh38.p7) (21q11.2)
AD
GWASdb2
1   publication(s)
See rs on genome
7 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 21NC_000021.9:g.14337293T>G
GRCh37.p13 chr 21NC_000021.8:g.15709614T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.219G=0.781
1000GenomesAmericanSub694T=0.620G=0.380
1000GenomesEast AsianSub1008T=0.317G=0.683
1000GenomesEuropeSub1006T=0.619G=0.381
1000GenomesGlobalStudy-wide5008T=0.423G=0.577
1000GenomesSouth AsianSub978T=0.460G=0.540
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.628G=0.372
The Genome Aggregation DatabaseAfricanSub8716T=0.279G=0.721
The Genome Aggregation DatabaseAmericanSub834T=0.660G=0.340
The Genome Aggregation DatabaseEast AsianSub1614T=0.337G=0.663
The Genome Aggregation DatabaseEuropeSub18444T=0.645G=0.354
The Genome Aggregation DatabaseGlobalStudy-wide29910T=0.521G=0.478
The Genome Aggregation DatabaseOtherSub302T=0.550G=0.450
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.446G=0.553
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.621G=0.379
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs28225820.00061alcohol dependence20201924

eQTL of rs2822582 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2822582 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr211575326415753417E06943650
chr211575358415753659E06943970
chr211575326415753417E07143650
chr211575358415753659E07143970
chr211575326415753417E07243650
chr211575326415753417E07443650
chr211575358415753659E07443970




Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr211575451715756862E06744903
chr211575451715756862E06844903
chr211575451715756862E06944903
chr211575451715756862E07044903
chr211575451715756862E07144903
chr211575451715756862E07244903
chr211575451715756862E07344903
chr211575451715756862E07444903
chr211575451715756862E08144903
chr211575451715756862E08244903