SNP Detail Info-rs2822582

Organism: Homo sapiens

Alleles: T>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0478 (14311/29910,GnomAD)
T==0446 (13001/29118,TOPMED)
T==0423 (2117/5008,1000G)
G=0372 (1435/3854,ALSPAC)
G=0379 (1405/3708,TWINSUK)

Position: chr21:14337293 (GRCh38.p7) (21q11.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 7 Enhancers around

Promoter: 10 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 21	NC_000021.9:g.14337293T>G
GRCh37.p13 chr 21	NC_000021.8:g.15709614T>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.219	G=0.781
1000Genomes	American	Sub	694	T=0.620	G=0.380
1000Genomes	East Asian	Sub	1008	T=0.317	G=0.683
1000Genomes	Europe	Sub	1006	T=0.619	G=0.381
1000Genomes	Global	Study-wide	5008	T=0.423	G=0.577
1000Genomes	South Asian	Sub	978	T=0.460	G=0.540
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.628	G=0.372
The Genome Aggregation Database	African	Sub	8716	T=0.279	G=0.721
The Genome Aggregation Database	American	Sub	834	T=0.660	G=0.340
The Genome Aggregation Database	East Asian	Sub	1614	T=0.337	G=0.663
The Genome Aggregation Database	Europe	Sub	18444	T=0.645	G=0.354
The Genome Aggregation Database	Global	Study-wide	29910	T=0.521	G=0.478
The Genome Aggregation Database	Other	Sub	302	T=0.550	G=0.450
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.446	G=0.553
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.621	G=0.379

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs2822582	0.00061	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr21	15753264	15753417	E069	43650
chr21	15753584	15753659	E069	43970
chr21	15753264	15753417	E071	43650
chr21	15753584	15753659	E071	43970
chr21	15753264	15753417	E072	43650
chr21	15753264	15753417	E074	43650
chr21	15753584	15753659	E074	43970

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr21	15754517	15756862	E067	44903
chr21	15754517	15756862	E068	44903
chr21	15754517	15756862	E069	44903
chr21	15754517	15756862	E070	44903
chr21	15754517	15756862	E071	44903
chr21	15754517	15756862	E072	44903
chr21	15754517	15756862	E073	44903
chr21	15754517	15756862	E074	44903
chr21	15754517	15756862	E081	44903
chr21	15754517	15756862	E082	44903

rs2822582