rs2837302

Homo sapiens
C>A / C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0454 (13600/29906,GnomAD)
C==0442 (12871/29118,TOPMED)
C==0494 (2472/5008,1000G)
C==0431 (1661/3854,ALSPAC)
C==0419 (1552/3708,TWINSUK)
chr21:39931970 (GRCh38.p7) (21q22.2)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 21NC_000021.9:g.39931970C>A
GRCh38.p7 chr 21NC_000021.9:g.39931970C>T
GRCh37.p13 chr 21NC_000021.8:g.41303895C>A
GRCh37.p13 chr 21NC_000021.8:g.41303895C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.450T=0.550
1000GenomesAmericanSub694C=0.370T=0.630
1000GenomesEast AsianSub1008C=0.655T=0.345
1000GenomesEuropeSub1006C=0.416T=0.584
1000GenomesGlobalStudy-wide5008C=0.494T=0.506
1000GenomesSouth AsianSub978C=0.550T=0.450
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.431T=0.569
The Genome Aggregation DatabaseAfricanSub8698C=0.470T=0.530
The Genome Aggregation DatabaseAmericanSub838C=0.330T=0.670
The Genome Aggregation DatabaseEast AsianSub1616C=0.636T=0.364
The Genome Aggregation DatabaseEuropeSub18454C=0.437T=0.562
The Genome Aggregation DatabaseGlobalStudy-wide29906C=0.454T=0.545
The Genome Aggregation DatabaseOtherSub300C=0.440T=0.560
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.442T=0.558
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.419T=0.581
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs28373020.00032alcohol dependence20201924

eQTL of rs2837302 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2837302 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.