SNP Detail Info-rs284046

Organism: Homo sapiens

Alleles: A>C

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C=0041 (1248/29958,GnomAD)
C=0035 (1027/29118,TOPMED)
C=0023 (113/5008,1000G)
C=0073 (282/3854,ALSPAC)
C=0067 (249/3708,TWINSUK)

Position: chr1:188456602 (GRCh38.p7) (1q31.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.188456602A>C
GRCh37.p13 chr 1	NC_000001.10:g.188425733A>C

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.998	C=0.002
1000Genomes	American	Sub	694	A=0.970	C=0.030
1000Genomes	East Asian	Sub	1008	A=1.000	C=0.000
1000Genomes	Europe	Sub	1006	A=0.938	C=0.062
1000Genomes	Global	Study-wide	5008	A=0.977	C=0.023
1000Genomes	South Asian	Sub	978	A=0.970	C=0.030
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.927	C=0.073
The Genome Aggregation Database	African	Sub	8730	A=0.990	C=0.010
The Genome Aggregation Database	American	Sub	836	A=0.970	C=0.030
The Genome Aggregation Database	East Asian	Sub	1618	A=1.000	C=0.000
The Genome Aggregation Database	Europe	Sub	18472	A=0.939	C=0.060
The Genome Aggregation Database	Global	Study-wide	29958	A=0.958	C=0.041
The Genome Aggregation Database	Other	Sub	302	A=0.930	C=0.070
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.964	C=0.035
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.933	C=0.067

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs284046	0.000628	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs284046