SNP Detail Info-rs2866619

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0112 (3350/29906,GnomAD)
A=0124 (3627/29118,TOPMED)
A=0199 (998/5008,1000G)
A=0031 (118/3854,ALSPAC)
A=0031 (115/3708,TWINSUK)

Position: chr16:76218244 (GRCh38.p7) (16q23.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 16	NC_000016.10:g.76218244G>A
GRCh37.p13 chr 16	NC_000016.9:g.76252142G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.750	A=0.250
1000Genomes	American	Sub	694	G=0.900	A=0.100
1000Genomes	East Asian	Sub	1008	G=0.605	A=0.395
1000Genomes	Europe	Sub	1006	G=0.965	A=0.035
1000Genomes	Global	Study-wide	5008	G=0.801	A=0.199
1000Genomes	South Asian	Sub	978	G=0.830	A=0.170
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.969	A=0.031
The Genome Aggregation Database	African	Sub	8708	G=0.784	A=0.216
The Genome Aggregation Database	American	Sub	834	G=0.900	A=0.100
The Genome Aggregation Database	East Asian	Sub	1584	G=0.586	A=0.414
The Genome Aggregation Database	Europe	Sub	18478	G=0.960	A=0.039
The Genome Aggregation Database	Global	Study-wide	29906	G=0.888	A=0.112
The Genome Aggregation Database	Other	Sub	302	G=0.980	A=0.020
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.875	A=0.124
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.969	A=0.031

PMID	Title	Author	Journal
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet

SNP ID	p-value	Traits	Study
rs2866619	2.38E-05	alcohol and nictotine co-dependence	20158304

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr16	76227712	76229397	E068	-22745
chr16	76227712	76229397	E071	-22745
chr16	76233308	76234058	E074	-18084

rs2866619