rs2886497

Homo sapiens
G>C / G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0307 (9212/29932,GnomAD)
T=0378 (11011/29118,TOPMED)
T=0359 (1798/5008,1000G)
T=0207 (798/3854,ALSPAC)
T=0198 (736/3708,TWINSUK)
chr10:23381413 (GRCh38.p7) (10p12.2)
AD
GWASCatalog
1   publication(s)
See rs on genome
9 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.23381413G>C
GRCh38.p7 chr 10NC_000010.11:g.23381413G>T
GRCh37.p13 chr 10NC_000010.10:g.23670342G>C
GRCh37.p13 chr 10NC_000010.10:g.23670342G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.347T=0.653
1000GenomesAmericanSub694G=0.530T=0.470
1000GenomesEast AsianSub1008G=0.820T=0.180
1000GenomesEuropeSub1006G=0.801T=0.199
1000GenomesGlobalStudy-wide5008G=0.641T=0.359
1000GenomesSouth AsianSub978G=0.770T=0.230
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.793T=0.207
The Genome Aggregation DatabaseAfricanSub8706G=0.419C=0.000
The Genome Aggregation DatabaseAmericanSub838G=0.610C=0.00,
The Genome Aggregation DatabaseEast AsianSub1618G=0.745C=0.000
The Genome Aggregation DatabaseEuropeSub18470G=0.820C=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29932G=0.692C=0.000
The Genome Aggregation DatabaseOtherSub300G=0.640C=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.621T=0.378
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.802T=0.198
PMID Title Author Journal
29071344Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.Zhou HJAMA Psychiatry

P-Value

SNP ID p-value Traits Study
rs28864976E-06alcohol dependence29071344

eQTL of rs2886497 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2886497 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10107089069107089134E070-49836
chr10107109009107109071E070-29899
chr10107109149107109199E070-29771
chr10107110705107110761E070-28209
chr10107111120107111333E070-27637
chr10107110705107110761E072-28209
chr10107111120107111333E072-27637
chr10107089069107089134E081-49836
chr10107098837107098887E081-40083