rs2886920

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0343 (10270/29932,GnomAD)
T=0301 (8790/29118,TOPMED)
T=0309 (1546/5008,1000G)
T=0427 (1645/3854,ALSPAC)
T=0414 (1536/3708,TWINSUK)
chr4:73761228 (GRCh38.p7) (4q13.3)
AD
GWASdb2
3   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.73761228C>T
GRCh37.p13 chr 4NC_000004.11:g.74626945C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.836T=0.164
1000GenomesAmericanSub694C=0.700T=0.300
1000GenomesEast AsianSub1008C=0.583T=0.417
1000GenomesEuropeSub1006C=0.614T=0.386
1000GenomesGlobalStudy-wide5008C=0.691T=0.309
1000GenomesSouth AsianSub978C=0.680T=0.320
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.573T=0.427
The Genome Aggregation DatabaseAfricanSub8718C=0.819T=0.181
The Genome Aggregation DatabaseAmericanSub836C=0.680T=0.320
The Genome Aggregation DatabaseEast AsianSub1610C=0.604T=0.396
The Genome Aggregation DatabaseEuropeSub18466C=0.584T=0.415
The Genome Aggregation DatabaseGlobalStudy-wide29932C=0.656T=0.343
The Genome Aggregation DatabaseOtherSub302C=0.640T=0.360
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.698T=0.301
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.586T=0.414
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res
22479352The role of inflammatory pathway genetic variation on maternal metabolic phenotypes during pregnancy.Urbanek MPLoS One
20018089Toward the identification of causal genes in complex diseases: a gene-centric joint test of significance combining genomic and transcriptomic data.Charlesworth JCBMC Proc

P-Value

SNP ID p-value Traits Study
rs28869202.52E-05alcohol dependence21314694

eQTL of rs2886920 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2886920 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction