rs2888697

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0064 (1940/29956,GnomAD)
A=0077 (2244/29118,TOPMED)
A=0070 (350/5008,1000G)
A=0052 (199/3854,ALSPAC)
A=0054 (201/3708,TWINSUK)
chr7:89396487 (GRCh38.p7) (7q21.13)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.89396487C>A
GRCh37.p13 chr 7NC_000007.13:g.89025801C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.887A=0.113
1000GenomesAmericanSub694C=0.950A=0.050
1000GenomesEast AsianSub1008C=0.941A=0.059
1000GenomesEuropeSub1006C=0.944A=0.056
1000GenomesGlobalStudy-wide5008C=0.930A=0.070
1000GenomesSouth AsianSub978C=0.950A=0.050
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.948A=0.052
The Genome Aggregation DatabaseAfricanSub8726C=0.893A=0.107
The Genome Aggregation DatabaseAmericanSub838C=0.920A=0.080
The Genome Aggregation DatabaseEast AsianSub1598C=0.952A=0.048
The Genome Aggregation DatabaseEuropeSub18492C=0.954A=0.045
The Genome Aggregation DatabaseGlobalStudy-wide29956C=0.935A=0.064
The Genome Aggregation DatabaseOtherSub302C=0.890A=0.110
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.922A=0.077
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.946A=0.054
PMID Title Author Journal
22072270Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.Wang KSJ Neural Transm (Vienna)

P-Value

SNP ID p-value Traits Study
rs28886977.68E-05alcohol withdrawal symptoms22072270

eQTL of rs2888697 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2888697 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.