rs2896294

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0430 (12875/29912,GnomAD)
T==0389 (11347/29118,TOPMED)
T==0478 (2394/5008,1000G)
T==0493 (1901/3854,ALSPAC)
T==0487 (1807/3708,TWINSUK)
chr14:94740810 (GRCh38.p7) (14q32.13)
AD
GWASdb2
1   publication(s)
See rs on genome
8 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.94740810T>C
GRCh37.p13 chr 14NC_000014.8:g.95207147T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.167C=0.833
1000GenomesAmericanSub694T=0.630C=0.370
1000GenomesEast AsianSub1008T=0.588C=0.412
1000GenomesEuropeSub1006T=0.527C=0.473
1000GenomesGlobalStudy-wide5008T=0.478C=0.522
1000GenomesSouth AsianSub978T=0.630C=0.370
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.493C=0.507
The Genome Aggregation DatabaseAfricanSub8698T=0.216C=0.784
The Genome Aggregation DatabaseAmericanSub836T=0.610C=0.390
The Genome Aggregation DatabaseEast AsianSub1614T=0.522C=0.478
The Genome Aggregation DatabaseEuropeSub18462T=0.515C=0.484
The Genome Aggregation DatabaseGlobalStudy-wide29912T=0.430C=0.569
The Genome Aggregation DatabaseOtherSub302T=0.440C=0.560
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.389C=0.610
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.487C=0.513
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs28962940.0003alcohol dependence20201924

eQTL of rs2896294 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2896294 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr149516103395161121E068-46026
chr149516462095164724E068-42423
chr149516080695160946E081-46201
chr149516103395161121E081-46026
chr149516618795166241E081-40906
chr149516637795166470E081-40677
chr149516662295166683E082-40464
chr149516673295166892E082-40255



Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr149523565195237146E06728504
chr149523470595235647E06827558
chr149523565195237146E06828504
chr149523470595235647E06927558
chr149523565195237146E07128504
chr149523565195237146E07228504
chr149523565195237146E07328504
chr149523565195237146E07428504
chr149523470595235647E08227558
chr149523565195237146E08228504