rs2905347

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0496 (14841/29916,GnomAD)
G=0469 (13680/29118,TOPMED)
G=0366 (1832/5008,1000G)
A==0387 (1491/3854,ALSPAC)
A==0406 (1507/3708,TWINSUK)
chr7:22580700 (GRCh38.p7) (7p15.3)
AD
GWASCatalog
1   publication(s)
See rs on genome
88 Enhancers around
4 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.22580700A>G
GRCh37.p13 chr 7NC_000007.13:g.22620319A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.707G=0.293
1000GenomesAmericanSub694A=0.490G=0.510
1000GenomesEast AsianSub1008A=0.932G=0.068
1000GenomesEuropeSub1006A=0.381G=0.619
1000GenomesGlobalStudy-wide5008A=0.634G=0.366
1000GenomesSouth AsianSub978A=0.600G=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.387G=0.613
The Genome Aggregation DatabaseAfricanSub8702A=0.662G=0.338
The Genome Aggregation DatabaseAmericanSub836A=0.480G=0.520
The Genome Aggregation DatabaseEast AsianSub1610A=0.937G=0.063
The Genome Aggregation DatabaseEuropeSub18466A=0.391G=0.608
The Genome Aggregation DatabaseGlobalStudy-wide29916A=0.503G=0.496
The Genome Aggregation DatabaseOtherSub302A=0.550G=0.450
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.530G=0.469
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.406G=0.594
PMID Title Author Journal
29071344Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.Zhou HJAMA Psychiatry

P-Value

SNP ID p-value Traits Study
rs29053476E-06alcohol dependence29071344

eQTL of rs2905347 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2905347 in Fetal Brain

Probe ID Position Gene beta p-value
cg18045685chr7:226294740.09825594364168584.9848e-20

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr72260085022601837E067-18482
chr72260190622602223E067-18096
chr72260224022602316E067-18003
chr72260243222605591E067-14728
chr72260085022601837E068-18482
chr72260190622602223E068-18096
chr72260224022602316E068-18003
chr72260243222605591E068-14728
chr72260560922605759E068-14560
chr72260577622606142E068-14177
chr72262553822626677E0685219
chr72262837622628497E0688057
chr72263031522630505E0689996
chr72264143122641787E06821112
chr72264180722642100E06821488
chr72264215822642235E06821839
chr72260017222600235E069-20084
chr72260042222600781E069-19538
chr72260085022601837E069-18482
chr72260190622602223E069-18096
chr72260224022602316E069-18003
chr72260243222605591E069-14728
chr72260560922605759E069-14560
chr72259939022600103E070-20216
chr72260017222600235E070-20084
chr72260042222600781E070-19538
chr72260085022601837E070-18482
chr72260190622602223E070-18096
chr72260224022602316E070-18003
chr72260243222605591E070-14728
chr72264020922640259E07019890
chr72264041222640492E07020093
chr72264055822641071E07020239
chr72264108122641304E07020762
chr72260085022601837E071-18482
chr72260190622602223E071-18096
chr72260224022602316E071-18003
chr72260619922606532E071-13787
chr72260656922606613E071-13706
chr72262750422628286E0717185
chr72262837622628497E0718057
chr72262894322630026E0718624
chr72263004122630091E0719722
chr72263031522630505E0719996
chr72264108122641304E07120762
chr72264143122641787E07121112
chr72264180722642100E07121488
chr72260560922605759E072-14560
chr72260085022601837E073-18482
chr72260243222605591E073-14728
chr72262894322630026E0738624
chr72263004122630091E0739722
chr72260243222605591E074-14728
chr72261168022611730E074-8589
chr72261173322611841E074-8478
chr72261191922612338E074-7981
chr72261638322616678E074-3641
chr72262553822626677E0745219
chr72262673622627415E0746417
chr72262750422628286E0747185
chr72262837622628497E0748057
chr72262894322630026E0748624
chr72263004122630091E0749722
chr72263031522630505E0749996
chr72260017222600235E081-20084
chr72260042222600781E081-19538
chr72260085022601837E081-18482
chr72260190622602223E081-18096
chr72260224022602316E081-18003
chr72260243222605591E081-14728
chr72261064422610709E081-9610
chr72261078822610939E081-9380
chr72261112422611164E081-9155
chr72263563322635683E08115314
chr72263616322636255E08115844
chr72263631722636369E08115998
chr72263666622636992E08116347
chr72264041222640492E08120093
chr72264108122641304E08120762
chr72264143122641787E08121112
chr72264180722642100E08121488
chr72264215822642235E08121839
chr72264256722642661E08122248
chr72259040222590502E082-29817
chr72259052322590767E082-29552
chr72260042222600781E082-19538
chr72262894322630026E0828624
chr72263004122630091E0829722










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr72258874022590222E067-30097
chr72258874022590222E068-30097
chr72258874022590222E070-30097
chr72258874022590222E082-30097