rs2909678

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0255 (7651/29922,GnomAD)
T==0304 (8868/29118,TOPMED)
T==0403 (2018/5008,1000G)
T==0118 (453/3854,ALSPAC)
T==0125 (463/3708,TWINSUK)
chr7:131649242 (GRCh38.p7) (7q32.3)
AD
GWASCatalog
1   publication(s)
See rs on genome
73 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.131649242T>C
GRCh37.p13 chr 7NC_000007.13:g.131334001T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.527C=0.473
1000GenomesAmericanSub694T=0.330C=0.670
1000GenomesEast AsianSub1008T=0.624C=0.376
1000GenomesEuropeSub1006T=0.128C=0.872
1000GenomesGlobalStudy-wide5008T=0.403C=0.597
1000GenomesSouth AsianSub978T=0.340C=0.660
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.118C=0.882
The Genome Aggregation DatabaseAfricanSub8678T=0.479C=0.521
The Genome Aggregation DatabaseAmericanSub836T=0.350C=0.650
The Genome Aggregation DatabaseEast AsianSub1614T=0.589C=0.411
The Genome Aggregation DatabaseEuropeSub18494T=0.119C=0.880
The Genome Aggregation DatabaseGlobalStudy-wide29922T=0.255C=0.744
The Genome Aggregation DatabaseOtherSub300T=0.160C=0.840
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.304C=0.695
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.125C=0.875
PMID Title Author Journal
27151647An association study revealed substantial effects of dominance, epistasis and substance dependence co-morbidity on alcohol dependence symptom count.Chen GAddict Biol

P-Value

SNP ID p-value Traits Study
rs29096781E-08alcohol dependence27151647

eQTL of rs2909678 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2909678 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7131284802131284915E067-49086
chr7131284980131286037E067-47964
chr7131292012131292843E067-41158
chr7131292909131293160E067-40841
chr7131313107131313221E067-20780
chr7131313231131313376E067-20625
chr7131313551131313601E067-20400
chr7131313608131313648E067-20353
chr7131376547131376652E06742546
chr7131284980131286037E068-47964
chr7131288879131291906E068-42095
chr7131292012131292843E068-41158
chr7131292909131293160E068-40841
chr7131305405131305945E068-28056
chr7131306103131306157E068-27844
chr7131306498131306738E068-27263
chr7131313107131313221E068-20780
chr7131313231131313376E068-20625
chr7131313551131313601E068-20400
chr7131313608131313648E068-20353
chr7131313759131313974E068-20027
chr7131328023131328063E068-5938
chr7131328122131328192E068-5809
chr7131339253131340102E0685252
chr7131373099131373149E06839098
chr7131373819131373896E06839818
chr7131376547131376652E06842546
chr7131284980131286037E069-47964
chr7131288879131291906E069-42095
chr7131284802131284915E070-49086
chr7131284980131286037E070-47964
chr7131288879131291906E070-42095
chr7131312319131312495E070-21506
chr7131312504131312886E070-21115
chr7131318095131318615E070-15386
chr7131318666131318847E070-15154
chr7131318866131318985E070-15016
chr7131377318131377482E07043317
chr7131377616131377672E07043615
chr7131377726131377794E07043725
chr7131284980131286037E071-47964
chr7131288879131291906E071-42095
chr7131305405131305945E071-28056
chr7131306103131306157E071-27844
chr7131376547131376652E07142546
chr7131284980131286037E072-47964
chr7131288879131291906E072-42095
chr7131339253131340102E0725252
chr7131376547131376652E07242546
chr7131288879131291906E073-42095
chr7131292012131292843E073-41158
chr7131292909131293160E073-40841
chr7131314867131314947E073-19054
chr7131314994131315062E073-18939
chr7131315232131315399E073-18602
chr7131284980131286037E074-47964
chr7131288879131291906E074-42095
chr7131292012131292843E074-41158
chr7131376547131376652E07442546
chr7131284980131286037E081-47964
chr7131286053131286103E081-47898
chr7131286392131286482E081-47519
chr7131286605131286877E081-47124
chr7131306103131306157E081-27844
chr7131339253131340102E0815252
chr7131376547131376652E08142546
chr7131377318131377482E08143317
chr7131284802131284915E082-49086
chr7131284980131286037E082-47964
chr7131318095131318615E082-15386
chr7131318666131318847E082-15154
chr7131318866131318985E082-15016
chr7131376547131376652E08242546