rs2915131

Homo sapiens
T>C
LOC105375147 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0427 (12790/29910,GnomAD)
C=0380 (11072/29118,TOPMED)
C=0343 (1718/5008,1000G)
T==0437 (1686/3854,ALSPAC)
T==0437 (1622/3708,TWINSUK)
chr7:9886401 (GRCh38.p7) (7p21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.9886401T>C
GRCh37.p13 chr 7NC_000007.13:g.9926030T>C

Gene: LOC105375147, uncharacterized LOC105375147(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105375147 transcriptXR_927026.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.842C=0.158
1000GenomesAmericanSub694T=0.610C=0.390
1000GenomesEast AsianSub1008T=0.748C=0.252
1000GenomesEuropeSub1006T=0.461C=0.539
1000GenomesGlobalStudy-wide5008T=0.657C=0.343
1000GenomesSouth AsianSub978T=0.550C=0.450
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.437C=0.563
The Genome Aggregation DatabaseAfricanSub8716T=0.760C=0.240
The Genome Aggregation DatabaseAmericanSub836T=0.580C=0.420
The Genome Aggregation DatabaseEast AsianSub1604T=0.766C=0.234
The Genome Aggregation DatabaseEuropeSub18452T=0.468C=0.531
The Genome Aggregation DatabaseGlobalStudy-wide29910T=0.572C=0.427
The Genome Aggregation DatabaseOtherSub302T=0.460C=0.540
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.619C=0.380
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.437C=0.563
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs29151312E-05alcoholism (heaviness of drinking)21529783

eQTL of rs2915131 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2915131 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.