rs2949081

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
T=0323 (9690/29922,GnomAD)
T=0308 (8995/29116,TOPMED)
T=0278 (1391/5008,1000G)
T=0382 (1474/3854,ALSPAC)
T=0364 (1348/3708,TWINSUK)
chr2:35944468 (GRCh38.p7) (2p22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
10 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.35944468T>G
GRCh37.p13 chr 2NC_000002.11:g.36169533G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.786T==0.214
1000GenomesAmericanSub694G=0.740T==0.260
1000GenomesEast AsianSub1008G=0.759T==0.241
1000GenomesEuropeSub1006G=0.590T==0.410
1000GenomesGlobalStudy-wide5008G=0.722T==0.278
1000GenomesSouth AsianSub978G=0.720T==0.280
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.618T==0.382
The Genome Aggregation DatabaseAfricanSub8714G=0.769T==0.231
The Genome Aggregation DatabaseAmericanSub834G=0.780T==0.220
The Genome Aggregation DatabaseEast AsianSub1610G=0.787T==0.213
The Genome Aggregation DatabaseEuropeSub18462G=0.619T==0.380
The Genome Aggregation DatabaseGlobalStudy-wide29922G=0.676T==0.323
The Genome Aggregation DatabaseOtherSub302G=0.600T==0.400
Trans-Omics for Precision MedicineGlobalStudy-wide29116G=0.691T==0.308
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.636T==0.364
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs29490810.000403alcohol dependence20201924

eQTL of rs2949081 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2949081 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr23619882036198887E06829287
chr23619893736199129E06829404
chr23621418736214645E06844654
chr23621471336214944E06845180
chr23617507736175121E0705544
chr23617530636175413E0705773
chr23617272236173230E0743189
chr23618836336188427E08218830
chr23618843736188537E08218904
chr23618857736188705E08219044