SNP Detail Info-rs3005191

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

GPR158 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0493 (14737/29892,GnomAD)
A==0488 (14231/29118,TOPMED)
A==0414 (2071/5008,1000G)
A==0495 (1906/3854,ALSPAC)
G=0478 (1774/3708,TWINSUK)

Position: chr10:25487247 (GRCh38.p7) (10p12.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 10	NC_000010.11:g.25487247A>G
GRCh37.p13 chr 10	NC_000010.10:g.25776176A>G

Molecule type	Change	Amino acid[Codon]	SO Term
GPR158 transcript	NM_020752.2:c.	N/A	Intron Variant
GPR158 transcript variant X2	XM_017016452.1:c.	N/A	Intron Variant
GPR158 transcript variant X1	XR_930512.2:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.480	G=0.520
1000Genomes	American	Sub	694	A=0.500	G=0.500
1000Genomes	East Asian	Sub	1008	A=0.178	G=0.822
1000Genomes	Europe	Sub	1006	A=0.492	G=0.508
1000Genomes	Global	Study-wide	5008	A=0.414	G=0.586
1000Genomes	South Asian	Sub	978	A=0.420	G=0.580
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.495	G=0.505
The Genome Aggregation Database	African	Sub	8698	A=0.506	G=0.494
The Genome Aggregation Database	American	Sub	836	A=0.500	G=0.500
The Genome Aggregation Database	East Asian	Sub	1606	A=0.225	G=0.775
The Genome Aggregation Database	Europe	Sub	18452	A=0.511	G=0.488
The Genome Aggregation Database	Global	Study-wide	29892	A=0.493	G=0.507
The Genome Aggregation Database	Other	Sub	300	A=0.380	G=0.620
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.488	G=0.511
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.522	G=0.478

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs3005191	0.000454	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs3005191