rs3015437

Homo sapiens
A>G
LOC100132735 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0471 (14122/29936,GnomAD)
G=0486 (14153/29118,TOPMED)
G=0462 (2312/5008,1000G)
A==0353 (1360/3854,ALSPAC)
A==0351 (1303/3708,TWINSUK)
chr6:139803938 (GRCh38.p7) (6q24.1)
ND
GWASdb2
1   publication(s)
See rs on genome
30 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.139803938A>G
GRCh37.p13 chr 6NC_000006.11:g.140125075A>G

Gene: LOC100132735, uncharacterized LOC100132735(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC100132735 transcriptNR_038399.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.724G=0.276
1000GenomesAmericanSub694A=0.320G=0.680
1000GenomesEast AsianSub1008A=0.553G=0.447
1000GenomesEuropeSub1006A=0.401G=0.599
1000GenomesGlobalStudy-wide5008A=0.538G=0.462
1000GenomesSouth AsianSub978A=0.570G=0.430
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.353G=0.647
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.513G=0.486
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.351G=0.649
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs30154370.000119nicotine dependence17158188

eQTL of rs3015437 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs3015437 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6140099135140099824E069-25251
chr6140097265140097608E070-27467
chr6140097643140097865E070-27210
chr6140097999140098129E070-26946
chr6140098414140098470E070-26605
chr6140098483140098728E070-26347
chr6140098806140098923E070-26152
chr6140098955140099008E070-26067
chr6140099065140099118E070-25957
chr6140099135140099824E070-25251
chr6140086375140086501E073-38574
chr6140097265140097608E081-27467
chr6140097643140097865E081-27210
chr6140097999140098129E081-26946
chr6140098414140098470E081-26605
chr6140098483140098728E081-26347
chr6140098806140098923E081-26152
chr6140098955140099008E081-26067
chr6140099065140099118E081-25957
chr6140099135140099824E081-25251
chr6140099861140100650E081-24425
chr6140097265140097608E082-27467
chr6140098414140098470E082-26605
chr6140098483140098728E082-26347
chr6140098806140098923E082-26152
chr6140098955140099008E082-26067
chr6140099065140099118E082-25957
chr6140099135140099824E082-25251
chr6140099861140100650E082-24425
chr6140100729140100861E082-24214