rs317031

Homo sapiens
C>A / C>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0457 (13620/29768,GnomAD)
G=0467 (13617/29118,TOPMED)
G=0461 (2310/5008,1000G)
G=0471 (1816/3854,ALSPAC)
G=0482 (1788/3708,TWINSUK)
chr4:35421494 (GRCh38.p7) (4p15.1)
ND
GWASdb2
1   publication(s)
See rs on genome
24 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.35421494C>A
GRCh38.p7 chr 4NC_000004.12:g.35421494C>G
GRCh37.p13 chr 4NC_000004.11:g.35423116C>A
GRCh37.p13 chr 4NC_000004.11:g.35423116C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.543G=0.457
1000GenomesAmericanSub694C=0.500G=0.500
1000GenomesEast AsianSub1008C=0.653G=0.347
1000GenomesEuropeSub1006C=0.560G=0.440
1000GenomesGlobalStudy-wide5008C=0.539G=0.461
1000GenomesSouth AsianSub978C=0.420G=0.580
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.529G=0.471
The Genome Aggregation DatabaseAfricanSub8698C=0.555G=0.445
The Genome Aggregation DatabaseAmericanSub830C=0.460G=0.54,
The Genome Aggregation DatabaseEast AsianSub1584C=0.687G=0.313
The Genome Aggregation DatabaseEuropeSub18354C=0.527G=0.472
The Genome Aggregation DatabaseGlobalStudy-wide29768C=0.542G=0.457
The Genome Aggregation DatabaseOtherSub302C=0.580G=0.42,
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.532G=0.467
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.518G=0.482
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs3170310.000302nicotine dependence17158188

eQTL of rs317031 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs317031 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4143272075143272468E06727093
chr4143272571143272882E06727589
chr4143286444143286494E06841462
chr4143286679143286860E06841697
chr4143271951143272060E06926969
chr4143272075143272468E06927093
chr4143286444143286494E06941462
chr4143286679143286860E06941697
chr4143272571143272882E07027589
chr4143272983143273515E07028001
chr4143271951143272060E07126969
chr4143272075143272468E07127093
chr4143272571143272882E07127589
chr4143286444143286494E07341462
chr4143286679143286860E07341697
chr4143273940143274223E07428958
chr4143274334143274725E07429352
chr4143274743143274868E07429761
chr4143286444143286494E08141462
chr4143287927143288334E08142945
chr4143288483143288569E08143501
chr4143286444143286494E08241462
chr4143286679143286860E08241697
chr4143293741143294357E08248759