SNP Detail Info-rs317047

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0462 (13765/29772,GnomAD)
G=0470 (13693/29118,TOPMED)
G=0465 (2329/5008,1000G)
G=0472 (1818/3854,ALSPAC)
G=0482 (1789/3708,TWINSUK)

Position: chr4:35433088 (GRCh38.p7) (4p15.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 4 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.35433088A>G
GRCh37.p13 chr 4	NC_000004.11:g.35434710A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.536	G=0.464
1000Genomes	American	Sub	694	A=0.500	G=0.500
1000Genomes	East Asian	Sub	1008	A=0.648	G=0.352
1000Genomes	Europe	Sub	1006	A=0.556	G=0.444
1000Genomes	Global	Study-wide	5008	A=0.535	G=0.465
1000Genomes	South Asian	Sub	978	A=0.420	G=0.580
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.528	G=0.472
The Genome Aggregation Database	African	Sub	8656	A=0.549	G=0.451
The Genome Aggregation Database	American	Sub	834	A=0.460	G=0.540
The Genome Aggregation Database	East Asian	Sub	1564	A=0.678	G=0.322
The Genome Aggregation Database	Europe	Sub	18416	A=0.523	G=0.476
The Genome Aggregation Database	Global	Study-wide	29772	A=0.537	G=0.462
The Genome Aggregation Database	Other	Sub	302	A=0.580	G=0.420
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.529	G=0.470
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.518	G=0.482

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs317047	0.000276	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr4	35465298	35465454	E069	30588
chr4	35465298	35465454	E071	30588
chr4	35465298	35465454	E074	30588

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr4	35466830	35466880	E067	32120
chr4	35466830	35466880	E069	32120
chr4	35466830	35466880	E071	32120
chr4	35466830	35466880	E072	32120

rs317047