rs33282

Homo sapiens
C>T
ARL15 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0291 (8670/29736,GnomAD)
C==0299 (8729/29118,TOPMED)
C==0370 (1851/5008,1000G)
C==0262 (1009/3854,ALSPAC)
C==0254 (940/3708,TWINSUK)
chr5:54235475 (GRCh38.p7) (5q11.2)
AD
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.54235475C>T
GRCh37.p13 chr 5NC_000005.9:g.53531305C>T

Gene: ARL15, ADP ribosylation factor like GTPase 15(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ARL15 transcriptNM_019087.2:c.N/AIntron Variant
ARL15 transcript variant X1XM_011543498.2:c.N/AIntron Variant
ARL15 transcript variant X2XM_011543499.2:c.N/AIntron Variant
ARL15 transcript variant X3XM_011543500.2:c.N/AIntron Variant
ARL15 transcript variant X4XM_017009598.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.304T=0.696
1000GenomesAmericanSub694C=0.470T=0.530
1000GenomesEast AsianSub1008C=0.552T=0.448
1000GenomesEuropeSub1006C=0.253T=0.747
1000GenomesGlobalStudy-wide5008C=0.370T=0.630
1000GenomesSouth AsianSub978C=0.320T=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.262T=0.738
The Genome Aggregation DatabaseAfricanSub8664C=0.311T=0.689
The Genome Aggregation DatabaseAmericanSub814C=0.470T=0.530
The Genome Aggregation DatabaseEast AsianSub1616C=0.584T=0.416
The Genome Aggregation DatabaseEuropeSub18340C=0.250T=0.749
The Genome Aggregation DatabaseGlobalStudy-wide29736C=0.291T=0.708
The Genome Aggregation DatabaseOtherSub302C=0.210T=0.790
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.299T=0.700
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.254T=0.746
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs332822.09E-06alcohol dependence (age at onset)24962325

eQTL of rs33282 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs33282 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr55352492153525456E068-5849
chr55357394153574185E06942636
chr55357422253574433E06942917
chr55351066653510874E070-20431
chr55351115053511650E070-19655
chr55351327153513323E070-17982
chr55357394153574185E07242636
chr55357422253574433E07242917
chr55357444553574505E07243140
chr55357422253574433E07442917
chr55357444553574505E07443140
chr55351066653510874E081-20431
chr55351115053511650E081-19655
chr55351115053511650E082-19655







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr55355060653550896E07119301