SNP Detail Info-rs336605

Organism: Homo sapiens

Alleles: G>T

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0249 (7448/29894,GnomAD)
G==0202 (5905/29118,TOPMED)
G==0312 (1561/5008,1000G)
G==0268 (1034/3854,ALSPAC)
G==0270 (1001/3708,TWINSUK)

Position: chr3:18614858 (GRCh38.p7) (3p24.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 3	NC_000003.12:g.18614858G>T
GRCh37.p13 chr 3	NC_000003.11:g.18656350G>T

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.078	T=0.922
1000Genomes	American	Sub	694	G=0.270	T=0.730
1000Genomes	East Asian	Sub	1008	G=0.508	T=0.492
1000Genomes	Europe	Sub	1006	G=0.300	T=0.700
1000Genomes	Global	Study-wide	5008	G=0.312	T=0.688
1000Genomes	South Asian	Sub	978	G=0.470	T=0.530
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.268	T=0.732
The Genome Aggregation Database	African	Sub	8706	G=0.114	T=0.886
The Genome Aggregation Database	American	Sub	836	G=0.270	T=0.730
The Genome Aggregation Database	East Asian	Sub	1596	G=0.550	T=0.450
The Genome Aggregation Database	Europe	Sub	18454	G=0.283	T=0.716
The Genome Aggregation Database	Global	Study-wide	29894	G=0.249	T=0.750
The Genome Aggregation Database	Other	Sub	302	G=0.390	T=0.610
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.202	T=0.797
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.270	T=0.730

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs336605	0.00041	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
cg10792120	chr13:78550373	EDNRB	0.0174104067130655	5.2722e-9

rs336605