rs34870220

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0044 (1322/29864,GnomAD)
T=0036 (1057/29116,TOPMED)
T=0028 (141/5008,1000G)
T=0064 (248/3854,ALSPAC)
T=0063 (234/3708,TWINSUK)
chr17:7181592 (GRCh38.p7) (17p13.1)
AD
GWASdb2
2   publication(s)
See rs on genome
76 Enhancers around
23 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.7181592C>T
GRCh37.p13 chr 17NC_000017.10:g.7084911C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.998T=0.002
1000GenomesAmericanSub694C=0.960T=0.040
1000GenomesEast AsianSub1008C=1.000T=0.000
1000GenomesEuropeSub1006C=0.934T=0.066
1000GenomesGlobalStudy-wide5008C=0.972T=0.028
1000GenomesSouth AsianSub978C=0.950T=0.050
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.936T=0.064
The Genome Aggregation DatabaseAfricanSub8712C=0.989T=0.011
The Genome Aggregation DatabaseAmericanSub826C=0.970T=0.030
The Genome Aggregation DatabaseEast AsianSub1620C=0.999T=0.001
The Genome Aggregation DatabaseEuropeSub18404C=0.935T=0.064
The Genome Aggregation DatabaseGlobalStudy-wide29864C=0.955T=0.044
The Genome Aggregation DatabaseOtherSub302C=0.960T=0.040
Trans-Omics for Precision MedicineGlobalStudy-wide29116C=0.963T=0.036
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.937T=0.063
PMID Title Author Journal
22481050Genetic influences on craving for alcohol.Agrawal AAddict Behav
27866268A genome-wide association study of essential hypertension in an Australian population using a DNA pooling approach.Fowdar JYMol Genet Genomics

P-Value

SNP ID p-value Traits Study
rs348702201.26E-05alcohol craving with or without dependence22481050

eQTL of rs34870220 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs34870220 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1770492317049281E068-35630
chr1770495647049759E068-35152
chr1770501747050283E068-34628
chr1771095407109646E06824629
chr1771096907110435E06824779
chr1771105147112172E06825603
chr1771121897112537E06827278
chr1771126277112799E06827716
chr1771128697112913E06827958
chr1771133617113573E06828450
chr1771135887113638E06828677
chr1771137087113764E06828797
chr1771138297113962E06828918
chr1771140297114215E06829118
chr1771322387132376E06847327
chr1770372567037520E069-47391
chr1770772087078770E069-6141
chr1770787947079094E069-5817
chr1771095407109646E06924629
chr1771105147112172E06925603
chr1771121897112537E06927278
chr1770769997077115E070-7796
chr1770772087078770E070-6141
chr1770787947079094E070-5817
chr1771068767107128E07021965
chr1771096907110435E07024779
chr1771105147112172E07025603
chr1771121897112537E07027278
chr1771164707116558E07031559
chr1770389807039295E071-45616
chr1771091097109430E07124198
chr1771095407109646E07124629
chr1770772087078770E072-6141
chr1770787947079094E072-5817
chr1771068767107128E07221965
chr1771096907110435E07224779
chr1771105147112172E07225603
chr1771121897112537E07227278
chr1771126277112799E07227716
chr1771105147112172E07325603
chr1771121897112537E07327278
chr1771126277112799E07327716
chr1770772087078770E081-6141
chr1770946137095371E0819702
chr1770953817095461E08110470
chr1770955587095885E08110647
chr1770960617096122E08111150
chr1770962437096283E08111332
chr1770965157096559E08111604
chr1770966547096727E08111743
chr1770967817096869E08111870
chr1771065917106828E08121680
chr1771068767107128E08121965
chr1771091097109430E08124198
chr1771095407109646E08124629
chr1771105147112172E08125603
chr1771140297114215E08129118
chr1771142677114410E08129356
chr1771144827116171E08129571
chr1771164707116558E08131559
chr1771343727134481E08149461
chr1770772087078770E082-6141
chr1770787947079094E082-5817
chr1770946137095371E0829702
chr1770953817095461E08210470
chr1770955587095885E08210647
chr1770960617096122E08211150
chr1770962437096283E08211332
chr1770965157096559E08211604
chr1770966547096727E08211743
chr1770967817096869E08211870
chr1771064267106537E08221515
chr1771065917106828E08221680
chr1771068767107128E08221965
chr1771096907110435E08224779
chr1771105147112172E08225603








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1770799647080259E067-4652
chr1770802837081901E067-3010
chr1771071407109069E06722229
chr1771071407109069E06822229
chr1770802837081901E069-3010
chr1771071407109069E06922229
chr1770799647080259E070-4652
chr1770802837081901E070-3010
chr1771071407109069E07022229
chr1770802837081901E071-3010
chr1771071407109069E07122229
chr1770799647080259E072-4652
chr1770802837081901E072-3010
chr1771071407109069E07222229
chr1770799647080259E073-4652
chr1770802837081901E073-3010
chr1771071407109069E07322229
chr1771071407109069E07422229
chr1770799647080259E081-4652
chr1770802837081901E081-3010
chr1770799647080259E082-4652
chr1770802837081901E082-3010
chr1771071407109069E08222229