rs350255

Homo sapiens
A>G
SNX29 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0326 (9771/29906,GnomAD)
A==0287 (8381/29118,TOPMED)
A==0251 (1256/5008,1000G)
A==0415 (1600/3854,ALSPAC)
A==0408 (1513/3708,TWINSUK)
chr16:12111685 (GRCh38.p7) (16p13.13)
AD
GWASdb2
1   publication(s)
See rs on genome
223 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.12111685A>G
GRCh37.p13 chr 16NC_000016.9:g.12205542A>G

Gene: SNX29, sorting nexin 29(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SNX29 transcriptNM_032167.4:c.N/AIntron Variant
SNX29 transcript variant X9XM_005255682.3:c.N/AIntron Variant
SNX29 transcript variant X12XM_005255683.3:c.N/AIntron Variant
SNX29 transcript variant X1XM_011522738.2:c.N/AIntron Variant
SNX29 transcript variant X5XM_011522741.2:c.N/AIntron Variant
SNX29 transcript variant X7XM_011522743.2:c.N/AIntron Variant
SNX29 transcript variant X10XM_011522744.2:c.N/AIntron Variant
SNX29 transcript variant X3XM_017023871.1:c.N/AIntron Variant
SNX29 transcript variant X4XM_017023872.1:c.N/AIntron Variant
SNX29 transcript variant X6XM_017023873.1:c.N/AIntron Variant
SNX29 transcript variant X8XM_017023874.1:c.N/AIntron Variant
SNX29 transcript variant X11XM_017023875.1:c.N/AIntron Variant
SNX29 transcript variant X13XM_017023876.1:c.N/AIntron Variant
SNX29 transcript variant X14XM_017023877.1:c.N/AIntron Variant
SNX29 transcript variant X15XM_017023878.1:c.N/AGenic Upstream Transcript Variant
SNX29 transcript variant X2XR_001752024.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.113G=0.887
1000GenomesAmericanSub694A=0.320G=0.680
1000GenomesEast AsianSub1008A=0.087G=0.913
1000GenomesEuropeSub1006A=0.393G=0.607
1000GenomesGlobalStudy-wide5008A=0.251G=0.749
1000GenomesSouth AsianSub978A=0.410G=0.590
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.415G=0.585
The Genome Aggregation DatabaseAfricanSub8718A=0.164G=0.836
The Genome Aggregation DatabaseAmericanSub836A=0.340G=0.660
The Genome Aggregation DatabaseEast AsianSub1610A=0.088G=0.912
The Genome Aggregation DatabaseEuropeSub18440A=0.424G=0.575
The Genome Aggregation DatabaseGlobalStudy-wide29906A=0.326G=0.673
The Genome Aggregation DatabaseOtherSub302A=0.280G=0.720
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.287G=0.712
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.408G=0.592
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs3502551.6E-05alcoholism (heaviness of drinking)21529783

eQTL of rs350255 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs350255 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr161215627712157047E067-48495
chr161218138712181474E067-24068
chr161218153012181611E067-23931
chr161218170312181843E067-23699
chr161218189312182262E067-23280
chr161218228312182422E067-23120
chr161218566212186867E067-18675
chr161218840912190625E067-14917
chr161219063612191043E067-14499
chr161219104612191925E067-13617
chr161219197912192051E067-13491
chr161220725312208132E0671711
chr161220827912208381E0672737
chr161221384212213924E0678300
chr161223501212235567E06729470
chr161223558412235933E06730042
chr161223598112236118E06730439
chr161224089312241189E06735351
chr161224134812242401E06735806
chr161225230212252795E06746760
chr161225285712252901E06747315
chr161225295512253216E06747413
chr161225327912253342E06747737
chr161225362212253758E06748080
chr161225389712253991E06748355
chr161215627712157047E068-48495
chr161216161812162118E068-43424
chr161218170312181843E068-23699
chr161218189312182262E068-23280
chr161218228312182422E068-23120
chr161218301512183083E068-22459
chr161218566212186867E068-18675
chr161218840912190625E068-14917
chr161219063612191043E068-14499
chr161219104612191925E068-13617
chr161219197912192051E068-13491
chr161220498512205035E068-507
chr161220521912205424E068-118
chr161220545412205532E068-10
chr161220593012206217E068388
chr161220622012206270E068678
chr161220629812206428E068756
chr161220668412206775E0681142
chr161220725312208132E0681711
chr161220827912208381E0682737
chr161224089312241189E06835351
chr161224123312241298E06835691
chr161225285712252901E06847315
chr161225295512253216E06847413
chr161225327912253342E06847737
chr161218153012181611E069-23931
chr161218170312181843E069-23699
chr161218189312182262E069-23280
chr161218566212186867E069-18675
chr161218840912190625E069-14917
chr161219063612191043E069-14499
chr161219104612191925E069-13617
chr161219197912192051E069-13491
chr161219214112192251E069-13291
chr161219225212192579E069-12963
chr161219268612192784E069-12758
chr161220725312208132E0691711
chr161220827912208381E0692737
chr161221343912213830E0697897
chr161221384212213924E0698300
chr161223558412235933E06930042
chr161223598112236118E06930439
chr161224089312241189E06935351
chr161225230212252795E06946760
chr161225285712252901E06947315
chr161225295512253216E06947413
chr161225327912253342E06947737
chr161218566212186867E070-18675
chr161218840912190625E070-14917
chr161219063612191043E070-14499
chr161219104612191925E070-13617
chr161219197912192051E070-13491
chr161221332712213384E0707785
chr161221400512214944E0708463
chr161221496712215114E0709425
chr161221511712215222E0709575
chr161224089312241189E07035351
chr161224123312241298E07035691
chr161224134812242401E07035806
chr161225285712252901E07047315
chr161225295512253216E07047413
chr161216161812162118E071-43424
chr161218445312184530E071-21012
chr161218566212186867E071-18675
chr161218686812186937E071-18605
chr161218696012187046E071-18496
chr161218840912190625E071-14917
chr161219063612191043E071-14499
chr161219104612191925E071-13617
chr161219197912192051E071-13491
chr161219214112192251E071-13291
chr161219225212192579E071-12963
chr161220629812206428E071756
chr161220668412206775E0711142
chr161220725312208132E0711711
chr161221343912213830E0717897
chr161221384212213924E0718300
chr161221400512214944E0718463
chr161221496712215114E0719425
chr161221511712215222E0719575
chr161221743912217489E07111897
chr161221771612217805E07112174
chr161223091012231525E07125368
chr161223152712232047E07125985
chr161223501212235567E07129470
chr161223558412235933E07130042
chr161224089312241189E07135351
chr161224123312241298E07135691
chr161224134812242401E07135806
chr161224619412246234E07140652
chr161225230212252795E07146760
chr161225285712252901E07147315
chr161225295512253216E07147413
chr161225327912253342E07147737
chr161215627712157047E072-48495
chr161216161812162118E072-43424
chr161218138712181474E072-24068
chr161218153012181611E072-23931
chr161218170312181843E072-23699
chr161218189312182262E072-23280
chr161218566212186867E072-18675
chr161218840912190625E072-14917
chr161219063612191043E072-14499
chr161219104612191925E072-13617
chr161219197912192051E072-13491
chr161219214112192251E072-13291
chr161219225212192579E072-12963
chr161219268612192784E072-12758
chr161220521912205424E072-118
chr161220545412205532E072-10
chr161220725312208132E0721711
chr161223558412235933E07230042
chr161223598112236118E07230439
chr161224134812242401E07235806
chr161225230212252795E07246760
chr161225285712252901E07247315
chr161225295512253216E07247413
chr161225327912253342E07247737
chr161218153012181611E073-23931
chr161218170312181843E073-23699
chr161218566212186867E073-18675
chr161218840912190625E073-14917
chr161219063612191043E073-14499
chr161219104612191925E073-13617
chr161220498512205035E073-507
chr161220521912205424E073-118
chr161221343912213830E0737897
chr161221384212213924E0738300
chr161221400512214944E0738463
chr161221496712215114E0739425
chr161224134812242401E07335806
chr161215627712157047E074-48495
chr161218153012181611E074-23931
chr161218170312181843E074-23699
chr161218566212186867E074-18675
chr161218686812186937E074-18605
chr161218696012187046E074-18496
chr161218840912190625E074-14917
chr161219063612191043E074-14499
chr161219104612191925E074-13617
chr161219197912192051E074-13491
chr161220668412206775E0741142
chr161220725312208132E0741711
chr161223501212235567E07429470
chr161223558412235933E07430042
chr161223598112236118E07430439
chr161224123312241298E07435691
chr161224134812242401E07435806
chr161224246112242513E07436919
chr161224302412243135E07437482
chr161224315312243197E07437611
chr161224599212246061E07440450
chr161224619412246234E07440652
chr161224668012246744E07441138
chr161224678112246864E07441239
chr161225230212252795E07446760
chr161225285712252901E07447315
chr161225295512253216E07447413
chr161225327912253342E07447737
chr161218840912190625E081-14917
chr161219063612191043E081-14499
chr161219104612191925E081-13617
chr161219214112192251E081-13291
chr161219225212192579E081-12963
chr161220725312208132E0811711
chr161221343912213830E0817897
chr161221384212213924E0818300
chr161221400512214944E0818463
chr161223091012231525E08125368
chr161223152712232047E08125985
chr161224089312241189E08135351
chr161224123312241298E08135691
chr161224134812242401E08135806
chr161225389712253991E08148355
chr161225423312254438E08148691
chr161225455112254728E08149009
chr161225474212254883E08149200
chr161225510612255203E08149564
chr161218566212186867E082-18675
chr161218686812186937E082-18605
chr161218696012187046E082-18496
chr161218840912190625E082-14917
chr161219063612191043E082-14499
chr161219104612191925E082-13617
chr161220725312208132E0821711
chr161220827912208381E0822737
chr161221400512214944E0828463
chr161223091012231525E08225368
chr161223152712232047E08225985
chr161224089312241189E08235351
chr161224123312241298E08235691
chr161224134812242401E08235806
chr161225285712252901E08247315
chr161225295512253216E08247413
chr161225423312254438E08248691
chr161225455112254728E08249009
chr161225474212254883E08249200
chr161225510612255203E08249564