rs351847

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0433 (12961/29916,GnomAD)
C=0494 (14402/29118,TOPMED)
C=0469 (2351/5008,1000G)
C=0351 (1352/3854,ALSPAC)
C=0348 (1292/3708,TWINSUK)
chr10:53584952 (GRCh38.p7) (10q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.53584952T>C
GRCh37.p13 chr 10NC_000010.10:g.55344712T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.272C=0.728
1000GenomesAmericanSub694T=0.670C=0.330
1000GenomesEast AsianSub1008T=0.661C=0.339
1000GenomesEuropeSub1006T=0.631C=0.369
1000GenomesGlobalStudy-wide5008T=0.531C=0.469
1000GenomesSouth AsianSub978T=0.540C=0.460
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.649C=0.351
The Genome Aggregation DatabaseAfricanSub8702T=0.351C=0.649
The Genome Aggregation DatabaseAmericanSub836T=0.730C=0.270
The Genome Aggregation DatabaseEast AsianSub1610T=0.686C=0.314
The Genome Aggregation DatabaseEuropeSub18466T=0.649C=0.350
The Genome Aggregation DatabaseGlobalStudy-wide29916T=0.566C=0.433
The Genome Aggregation DatabaseOtherSub302T=0.640C=0.360
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.505C=0.494
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.652C=0.348
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs3518470.000454alcohol dependence20201924

eQTL of rs351847 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs351847 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.