rs35616138

Homo sapiens
A>G / A>T
LOC107984269 : Non Coding Transcript Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0048 (1465/29976,GnomAD)
T=0045 (1310/29118,TOPMED)
T=0047 (237/5008,1000G)
T=0080 (307/3854,ALSPAC)
T=0074 (275/3708,TWINSUK)
chr10:113460253 (GRCh38.p7) (10q25.3)
AD
GWASdb2
1   publication(s)
See rs on genome
35 Enhancers around
11 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.113460253A>G
GRCh38.p7 chr 10NC_000010.11:g.113460253A>T
GRCh37.p13 chr 10NC_000010.10:g.115220012A>G
GRCh37.p13 chr 10NC_000010.10:g.115220012A>T

Gene: LOC107984269, uncharacterized LOC107984269(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC107984269 transcript variant X1XR_001747589.1:n....XR_001747589.1:n.5764A>GA>GNon Coding Transcript Variant
LOC107984269 transcript variant X1XR_001747589.1:n....XR_001747589.1:n.5764A>TA>TNon Coding Transcript Variant
LOC107984269 transcript variant X2XR_001747590.1:n....XR_001747590.1:n.5764A>GA>GNon Coding Transcript Variant
LOC107984269 transcript variant X2XR_001747590.1:n....XR_001747590.1:n.5764A>TA>TNon Coding Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.996T=0.004
1000GenomesAmericanSub694A=0.980T=0.020
1000GenomesEast AsianSub1008A=0.907T=0.093
1000GenomesEuropeSub1006A=0.935T=0.065
1000GenomesGlobalStudy-wide5008A=0.953T=0.047
1000GenomesSouth AsianSub978A=0.940T=0.060
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.920T=0.080
The Genome Aggregation DatabaseAfricanSub8732A=0.986T=0.014
The Genome Aggregation DatabaseAmericanSub836A=0.970T=0.03,
The Genome Aggregation DatabaseEast AsianSub1622A=0.924T=0.076
The Genome Aggregation DatabaseEuropeSub18484A=0.936T=0.063
The Genome Aggregation DatabaseGlobalStudy-wide29976A=0.951T=0.048
The Genome Aggregation DatabaseOtherSub302A=0.920T=0.08,
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.955T=0.045
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.926T=0.074
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs356161382.64E-05alcohol consumption23743675

eQTL of rs35616138 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs35616138 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr109404890494048958E067-31027
chr109406363794063749E067-16236
chr109406387594063948E067-16037
chr109409510094095165E06715115
chr109406329194063341E068-16644
chr109406363794063749E068-16236
chr109406387594063948E068-16037
chr109406967094069720E068-10265
chr109406983794070092E068-9893
chr109405298594053069E070-26916
chr109406311294063172E070-16813
chr109406329194063341E070-16644
chr109405294294052982E071-27003
chr109405298594053069E071-26916
chr109407475494074855E071-5130
chr109407494194074991E071-4994
chr109410499494105193E07125009
chr109406329194063341E072-16644
chr109406387594063948E072-16037
chr109405294294052982E073-27003
chr109406363794063749E073-16236
chr109406387594063948E073-16037
chr109406329194063341E074-16644
chr109406363794063749E074-16236
chr109407475494074855E074-5130
chr109407494194074991E074-4994
chr109405294294052982E082-27003
chr109405298594053069E082-26916
chr109405340094053441E082-26544
chr109405355394053593E082-26392
chr109405375394054011E082-25974
chr109405407994054189E082-25796
chr109405427894054363E082-25622
chr109405443394054489E082-25496
chr109405468094054730E082-25255








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr109404982094052571E067-27414
chr109404982094052571E068-27414
chr109404982094052571E069-27414
chr109404982094052571E070-27414
chr109404982094052571E071-27414
chr109404982094052571E072-27414
chr109404982094052571E073-27414
chr109403884494039388E074-40597
chr109404982094052571E074-27414
chr109404982094052571E081-27414
chr109404982094052571E082-27414