rs35626

Homo sapiens
G>T
ABCC1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0394 (11782/29888,GnomAD)
T=0448 (13046/29118,TOPMED)
T=0418 (2094/5008,1000G)
T=0299 (1151/3854,ALSPAC)
T=0323 (1196/3708,TWINSUK)
chr16:16076758 (GRCh38.p7) (16p13.11)
AD
GWASdb2
1   publication(s)
See rs on genome
16 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.16076758G>T
GRCh37.p13 chr 16NC_000016.9:g.16170615G>T
ABCC1 RefSeqGeneNG_028268.1:g.132182G>T
GRCh38.p7 chr 16 alt locus HSCHR16_1_CTG1NT_187607.1:g.1734610T>G

Gene: ABCC1, ATP binding cassette subfamily C member 1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ABCC1 transcriptNM_004996.3:c.N/AIntron Variant
ABCC1 transcript variant X2XM_011522497.1:c.N/AIntron Variant
ABCC1 transcript variant X5XM_011522498.2:c.N/AIntron Variant
ABCC1 transcript variant X1XM_017023237.1:c.N/AIntron Variant
ABCC1 transcript variant X3XM_017023238.1:c.N/AIntron Variant
ABCC1 transcript variant X4XM_017023239.1:c.N/AIntron Variant
ABCC1 transcript variant X6XM_017023240.1:c.N/AIntron Variant
ABCC1 transcript variant X7XM_017023241.1:c.N/AIntron Variant
ABCC1 transcript variant X8XM_017023242.1:c.N/AIntron Variant
ABCC1 transcript variant X9XM_017023243.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.352T=0.648
1000GenomesAmericanSub694G=0.710T=0.290
1000GenomesEast AsianSub1008G=0.637T=0.363
1000GenomesEuropeSub1006G=0.687T=0.313
1000GenomesGlobalStudy-wide5008G=0.582T=0.418
1000GenomesSouth AsianSub978G=0.630T=0.370
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.701T=0.299
The Genome Aggregation DatabaseAfricanSub8678G=0.399T=0.601
The Genome Aggregation DatabaseAmericanSub836G=0.720T=0.280
The Genome Aggregation DatabaseEast AsianSub1618G=0.642T=0.358
The Genome Aggregation DatabaseEuropeSub18454G=0.693T=0.306
The Genome Aggregation DatabaseGlobalStudy-wide29888G=0.605T=0.394
The Genome Aggregation DatabaseOtherSub302G=0.660T=0.340
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.552T=0.448
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.677T=0.323
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs356260.000826alcohol consumption (maxi-drinks)24277619

eQTL of rs35626 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr16:16170615MPV17LENSG00000156968.8G>T2.4093e-2681004Frontal_Cortex_BA9

meQTL of rs35626 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr161618673416186803E07016119
chr161618697616187053E07016361
chr161618705416187830E07016439
chr161616550616166035E071-4580
chr161621359216213698E07142977
chr161613015116130749E072-39866
chr161618981416189922E07419199
chr161618996516190005E07419350
chr161619008516190854E07419470
chr161613521016135746E081-34869
chr161613588816136323E081-34292
chr161613649016136544E081-34071
chr161613659516136645E081-33970
chr161613672216136776E081-33839
chr161613500516135201E082-35414
chr161613521016135746E082-34869