rs35738462

Homo sapiens
T>A / T>C
DAB1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0375 (11209/29826,GnomAD)
C=0363 (10594/29118,TOPMED)
C=0380 (1903/5008,1000G)
chr1:57790872 (GRCh38.p7) (1p32.2)
AD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
38 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.57790872T>A
GRCh38.p7 chr 1NC_000001.11:g.57790872T>C
GRCh37.p13 chr 1NC_000001.10:g.58256544T>A
GRCh37.p13 chr 1NC_000001.10:g.58256544T>C
DAB1 RefSeqGeneNG_046914.1:g.464668A>T
DAB1 RefSeqGeneNG_046914.1:g.464668A>G

Gene: DAB1, DAB1, reelin adaptor protein(minus strand)

Molecule type Change Amino acid[Codon] SO Term
DAB1 transcriptNM_021080.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.719C=0.281
1000GenomesAmericanSub694T=0.690C=0.310
1000GenomesEast AsianSub1008T=0.658C=0.342
1000GenomesEuropeSub1006T=0.542C=0.458
1000GenomesGlobalStudy-wide5008T=0.620C=0.380
1000GenomesSouth AsianSub978T=0.480C=0.520
The Genome Aggregation DatabaseAfricanSub8678T=0.722C=0.278
The Genome Aggregation DatabaseAmericanSub838T=0.700C=0.300
The Genome Aggregation DatabaseEast AsianSub1606T=0.647C=0.353
The Genome Aggregation DatabaseEuropeSub18402T=0.574C=0.425
The Genome Aggregation DatabaseGlobalStudy-wide29826T=0.624C=0.375
The Genome Aggregation DatabaseOtherSub302T=0.490C=0.510
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.636C=0.363
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs357384622E-06alcohol dependence (age at onset)24962325

eQTL of rs35738462 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs35738462 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr15808849058088591E067-26157
chr15808874658089091E067-25657
chr15806477258064848E070-49900
chr15806489458065477E070-49271
chr15806549958065733E070-49015
chr15806583358065926E070-48822
chr15808849058088591E071-26157
chr15808874658089091E071-25657
chr15808927758089375E071-25373
chr15806477258064848E081-49900
chr15806489458065477E081-49271
chr15806549958065733E081-49015
chr15806583358065926E081-48822
chr15806593758066418E081-48330
chr15808638658086588E081-28160
chr15808674758086830E081-27918
chr15808686458086950E081-27798
chr15808700358087078E081-27670
chr15808761658087758E081-26990
chr15808849058088591E081-26157
chr15808874658089091E081-25657
chr15808927758089375E081-25373
chr15808951958089685E081-25063
chr15809874358098819E081-15929
chr15809882858099030E081-15718
chr15809903558099190E081-15558
chr15816360658163749E08148858
chr15806477258064848E082-49900
chr15806489458065477E082-49271
chr15808620658086381E082-28367
chr15808638658086588E082-28160
chr15808849058088591E082-26157
chr15808874658089091E082-25657
chr15808927758089375E082-25373
chr15808951958089685E082-25063
chr15809874358098819E082-15929
chr15809882858099030E082-15718
chr15809903558099190E082-15558