rs35852281

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0109 (3282/29898,GnomAD)
T=0095 (2777/29118,TOPMED)
T=0090 (452/5008,1000G)
T=0138 (533/3854,ALSPAC)
T=0135 (499/3708,TWINSUK)
chr15:36228793 (GRCh38.p7) (15q14)
AD
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.36228793C>T
GRCh37.p13 chr 15NC_000015.9:g.36520994C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.952T=0.048
1000GenomesAmericanSub694C=0.960T=0.040
1000GenomesEast AsianSub1008C=0.962T=0.038
1000GenomesEuropeSub1006C=0.851T=0.149
1000GenomesGlobalStudy-wide5008C=0.910T=0.090
1000GenomesSouth AsianSub978C=0.820T=0.180
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.862T=0.138
The Genome Aggregation DatabaseAfricanSub8718C=0.937T=0.063
The Genome Aggregation DatabaseAmericanSub834C=0.940T=0.060
The Genome Aggregation DatabaseEast AsianSub1604C=0.956T=0.044
The Genome Aggregation DatabaseEuropeSub18440C=0.859T=0.140
The Genome Aggregation DatabaseGlobalStudy-wide29898C=0.890T=0.109
The Genome Aggregation DatabaseOtherSub302C=0.910T=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.904T=0.095
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.865T=0.135
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs358522810.00089alcohol dependence20201924

eQTL of rs35852281 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs35852281 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr153648643736486487E067-34507
chr153654829036548437E06727296
chr153654857436548736E06727580
chr153648643736486487E069-34507
chr153654829036548437E06927296
chr153654857436548736E06927580
chr153654878536549060E06927791
chr153647100736471087E070-49907
chr153651121036511286E071-9708
chr153651129936511394E071-9600
chr153654829036548437E07127296
chr153654857436548736E07127580
chr153654857436548736E07427580
chr153654878536549060E07427791