rs35866478

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0062 (1869/29822,GnomAD)
A=0044 (1283/29118,TOPMED)
A=0108 (539/5008,1000G)
A=0060 (233/3854,ALSPAC)
A=0048 (178/3708,TWINSUK)
chr8:100795137 (GRCh38.p7) (8q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
20 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.100795137G>A
GRCh37.p13 chr 8NC_000008.10:g.101807365G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.995A=0.005
1000GenomesAmericanSub694G=0.830A=0.170
1000GenomesEast AsianSub1008G=0.710A=0.290
1000GenomesEuropeSub1006G=0.949A=0.051
1000GenomesGlobalStudy-wide5008G=0.892A=0.108
1000GenomesSouth AsianSub978G=0.930A=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.940A=0.060
The Genome Aggregation DatabaseAfricanSub8680G=0.984A=0.016
The Genome Aggregation DatabaseAmericanSub836G=0.810A=0.190
The Genome Aggregation DatabaseEast AsianSub1622G=0.686A=0.314
The Genome Aggregation DatabaseEuropeSub18382G=0.942A=0.057
The Genome Aggregation DatabaseGlobalStudy-wide29822G=0.937A=0.062
The Genome Aggregation DatabaseOtherSub302G=0.950A=0.050
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.955A=0.044
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.952A=0.048
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs358664783.43E-05alcohol consumption23743675

eQTL of rs35866478 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs35866478 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8101773554101775046E068-32319
chr8101847470101848214E06840105
chr8101762717101763214E071-44151
chr8101764400101764498E071-42867
chr8101764560101764751E071-42614
chr8101764770101764823E071-42542
chr8101803597101803661E072-3704
chr8101803758101804338E074-3027
chr8101804391101804510E074-2855
chr8101847470101848214E07440105
chr8101848259101848339E07440894
chr8101775773101775823E081-31542
chr8101775832101775882E081-31483
chr8101775951101776079E081-31286
chr8101803597101803661E081-3704
chr8101803758101804338E081-3027
chr8101804391101804510E081-2855
chr8101851627101851825E08144262
chr8101851845101851917E08144480
chr8101775334101775644E082-31721