rs35878075

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0403 (12071/29946,GnomAD)
A=0360 (10492/29118,TOPMED)
A=0427 (2137/5008,1000G)
A=0456 (1756/3854,ALSPAC)
A=0471 (1745/3708,TWINSUK)
chr2:129237928 (GRCh38.p7) (2q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
16 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.129237928G>A
GRCh37.p13 chr 2NC_000002.11:g.129995501G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.816A=0.184
1000GenomesAmericanSub694G=0.480A=0.520
1000GenomesEast AsianSub1008G=0.297A=0.703
1000GenomesEuropeSub1006G=0.569A=0.431
1000GenomesGlobalStudy-wide5008G=0.573A=0.427
1000GenomesSouth AsianSub978G=0.600A=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.544A=0.456
The Genome Aggregation DatabaseAfricanSub8714G=0.772A=0.228
The Genome Aggregation DatabaseAmericanSub838G=0.470A=0.530
The Genome Aggregation DatabaseEast AsianSub1620G=0.223A=0.777
The Genome Aggregation DatabaseEuropeSub18472G=0.552A=0.447
The Genome Aggregation DatabaseGlobalStudy-wide29946G=0.596A=0.403
The Genome Aggregation DatabaseOtherSub302G=0.620A=0.380
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.639A=0.360
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.529A=0.471
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs358780756.78E-06alcohol dependence (age at onset)24962325

eQTL of rs35878075 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs35878075 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2129990903129991022E070-4479
chr2129991443129991904E070-3597
chr2129990903129991022E081-4479
chr2129991443129991904E081-3597
chr2129996773129997036E0811272
chr2130010223130010353E08114722
chr2130010398130011293E08114897
chr2130038915130039052E08143414
chr2130039472130039687E08143971
chr2130039843130039996E08144342
chr2129996773129997036E0821272
chr2130010223130010353E08214722
chr2130038591130038845E08243090
chr2130038915130039052E08243414
chr2130039472130039687E08243971
chr2130039843130039996E08244342