rs35951

Homo sapiens
G>T
ARL15 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0266 (7977/29942,GnomAD)
G==0306 (8913/29118,TOPMED)
G==0381 (1907/5008,1000G)
G==0162 (625/3854,ALSPAC)
G==0156 (577/3708,TWINSUK)
chr5:54296531 (GRCh38.p7) (5q11.2)
AD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
26 Enhancers around
11 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.54296531G>T
GRCh37.p13 chr 5NC_000005.9:g.53592361G>T

Gene: ARL15, ADP ribosylation factor like GTPase 15(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ARL15 transcriptNM_019087.2:c.N/AIntron Variant
ARL15 transcript variant X1XM_011543498.2:c.N/AIntron Variant
ARL15 transcript variant X2XM_011543499.2:c.N/AIntron Variant
ARL15 transcript variant X3XM_011543500.2:c.N/AIntron Variant
ARL15 transcript variant X4XM_017009598.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.469T=0.531
1000GenomesAmericanSub694G=0.450T=0.550
1000GenomesEast AsianSub1008G=0.532T=0.468
1000GenomesEuropeSub1006G=0.154T=0.846
1000GenomesGlobalStudy-wide5008G=0.381T=0.619
1000GenomesSouth AsianSub978G=0.290T=0.710
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.162T=0.838
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.306T=0.693
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.156T=0.844
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs359511E-08alcohol dependence (age at onset)24962325

eQTL of rs35951 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs35951 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr55359219153592302E067-59
chr55359230553592489E0670
chr55360474653604828E06712385
chr55359156353591979E068-382
chr55359219153592302E068-59
chr55359230553592489E0680
chr55357394153574185E069-18176
chr55357422253574433E069-17928
chr55360335753603465E07010996
chr55360351753603786E07011156
chr55360440353604546E07012042
chr55360474653604828E07112385
chr55357394153574185E072-18176
chr55357422253574433E072-17928
chr55357444553574505E072-17856
chr55357422253574433E074-17928
chr55357444553574505E074-17856
chr55359119253591246E074-1115
chr55359156353591979E074-382
chr55359219153592302E074-59
chr55359230553592489E0740
chr55360351753603786E08111156
chr55360427953604329E08111918
chr55360440353604546E08112042
chr55360474653604828E08112385
chr55360803253608085E08115671








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr55360503053607991E06712669
chr55360503053607991E06812669
chr55360503053607991E06912669
chr55360503053607991E07012669
chr55355060653550896E071-41465
chr55360503053607991E07112669
chr55360503053607991E07212669
chr55360503053607991E07312669
chr55360503053607991E07412669
chr55360503053607991E08112669
chr55360503053607991E08212669