rs36065736

Homo sapiens
G>A
IMPAD1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0243 (7298/29926,GnomAD)
A=0276 (8053/29118,TOPMED)
A=0307 (1538/5008,1000G)
A=0185 (712/3854,ALSPAC)
A=0183 (680/3708,TWINSUK)
chr8:56985796 (GRCh38.p7) (8q12.1)
AD
GWASCatalog
1   publication(s)
See rs on genome
207 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.56985796G>A
GRCh37.p13 chr 8NC_000008.10:g.57898355G>A
IMPAD1 RefSeqGeneNG_031926.1:g.13076C>T

Gene: IMPAD1, inositol monophosphatase domain containing 1(minus strand)

Molecule type Change Amino acid[Codon] SO Term
IMPAD1 transcriptNM_017813.4:c.N/AIntron Variant
IMPAD1 transcript variant X1XR_928786.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.646A=0.354
1000GenomesAmericanSub694G=0.690A=0.310
1000GenomesEast AsianSub1008G=0.567A=0.433
1000GenomesEuropeSub1006G=0.827A=0.173
1000GenomesGlobalStudy-wide5008G=0.693A=0.307
1000GenomesSouth AsianSub978G=0.750A=0.250
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.815A=0.185
The Genome Aggregation DatabaseAfricanSub8710G=0.645A=0.355
The Genome Aggregation DatabaseAmericanSub838G=0.690A=0.310
The Genome Aggregation DatabaseEast AsianSub1610G=0.519A=0.481
The Genome Aggregation DatabaseEuropeSub18466G=0.829A=0.170
The Genome Aggregation DatabaseGlobalStudy-wide29926G=0.756A=0.243
The Genome Aggregation DatabaseOtherSub302G=0.900A=0.100
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.723A=0.276
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.817A=0.183
PMID Title Author Journal
24166409Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs360657363E-07alcohol dependence24166409

eQTL of rs36065736 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs36065736 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr85785680457857027E067-41328
chr85789651257896552E067-1803
chr85789665857896727E067-1628
chr85789679857896842E067-1513
chr85789692257896997E067-1358
chr85789726157897368E067-987
chr85789745557897505E067-850
chr85789810457898148E067-207
chr85789816657898216E067-139
chr85789850157898545E067146
chr85789858057898640E067225
chr85789928357899333E067928
chr85789943057899470E0671075
chr85789948457899528E0671129
chr85790010657900233E0671751
chr85790086657901022E0672511
chr85790105157901116E0672696
chr85790117557901340E0672820
chr85790212157902220E0673766
chr85790230457902354E0673949
chr85790257157902611E0674216
chr85790274357902783E0674388
chr85790294657903011E0674591
chr85794250657943071E06744151
chr85794322657943517E06744871
chr85789596557896156E068-2199
chr85789624557896364E068-1991
chr85789651257896552E068-1803
chr85789665857896727E068-1628
chr85789679857896842E068-1513
chr85789816657898216E068-139
chr85789850157898545E068146
chr85789858057898640E068225
chr85789928357899333E068928
chr85789943057899470E0681075
chr85789948457899528E0681129
chr85790010657900233E0681751
chr85790086657901022E0682511
chr85790105157901116E0682696
chr85790117557901340E0682820
chr85790212157902220E0683766
chr85790230457902354E0683949
chr85790257157902611E0684216
chr85790274357902783E0684388
chr85790294657903011E0684591
chr85790340457903444E0685049
chr85789596557896156E069-2199
chr85789624557896364E069-1991
chr85789651257896552E069-1803
chr85789665857896727E069-1628
chr85789679857896842E069-1513
chr85789692257896997E069-1358
chr85789745557897505E069-850
chr85789810457898148E069-207
chr85789816657898216E069-139
chr85789850157898545E069146
chr85789858057898640E069225
chr85789928357899333E069928
chr85789943057899470E0691075
chr85789948457899528E0691129
chr85790010657900233E0691751
chr85790086657901022E0692511
chr85790105157901116E0692696
chr85790117557901340E0692820
chr85790212157902220E0693766
chr85790230457902354E0693949
chr85790257157902611E0694216
chr85790274357902783E0694388
chr85790294657903011E0694591
chr85790340457903444E0695049
chr85790734957907409E0698994
chr85790743457907623E0699079
chr85790768457907738E0699329
chr85792251957922657E06924164
chr85792287657923560E06924521
chr85792699057927496E06928635
chr85792760657927656E06929251
chr85794250657943071E06944151
chr85794322657943517E06944871
chr85790734957907409E0708994
chr85792685157926920E07028496
chr85792699057927496E07028635
chr85792760657927656E07029251
chr85792799857928165E07029643
chr85792818657928269E07029831
chr85785680457857027E071-41328
chr85785739157857440E071-40915
chr85785758357857627E071-40728
chr85785841957858473E071-39882
chr85789014157890433E071-7922
chr85789624557896364E071-1991
chr85789651257896552E071-1803
chr85789665857896727E071-1628
chr85789679857896842E071-1513
chr85789692257896997E071-1358
chr85789810457898148E071-207
chr85789816657898216E071-139
chr85789850157898545E071146
chr85789858057898640E071225
chr85789928357899333E071928
chr85789943057899470E0711075
chr85789948457899528E0711129
chr85790010657900233E0711751
chr85790086657901022E0712511
chr85790105157901116E0712696
chr85790117557901340E0712820
chr85790212157902220E0713766
chr85790230457902354E0713949
chr85790257157902611E0714216
chr85790274357902783E0714388
chr85790294657903011E0714591
chr85790734957907409E0718994
chr85790743457907623E0719079
chr85792760657927656E07129251
chr85792799857928165E07129643
chr85792818657928269E07129831
chr85794250657943071E07144151
chr85785739157857440E072-40915
chr85785758357857627E072-40728
chr85785841957858473E072-39882
chr85789651257896552E072-1803
chr85789665857896727E072-1628
chr85789679857896842E072-1513
chr85789692257896997E072-1358
chr85789928357899333E072928
chr85789943057899470E0721075
chr85789948457899528E0721129
chr85790086657901022E0722511
chr85790105157901116E0722696
chr85790117557901340E0722820
chr85790212157902220E0723766
chr85790230457902354E0723949
chr85790257157902611E0724216
chr85790274357902783E0724388
chr85790294657903011E0724591
chr85790340457903444E0725049
chr85792699057927496E07228635
chr85792760657927656E07229251
chr85787274257872845E073-25510
chr85789596557896156E073-2199
chr85789624557896364E073-1991
chr85789651257896552E073-1803
chr85789665857896727E073-1628
chr85789679857896842E073-1513
chr85789692257896997E073-1358
chr85789726157897368E073-987
chr85789850157898545E073146
chr85789858057898640E073225
chr85790010657900233E0731751
chr85790257157902611E0734216
chr85790274357902783E0734388
chr85790294657903011E0734591
chr85790340457903444E0735049
chr85785739157857440E074-40915
chr85785758357857627E074-40728
chr85785841957858473E074-39882
chr85787274257872845E074-25510
chr85789014157890433E074-7922
chr85789061757890658E074-7697
chr85789596557896156E074-2199
chr85789624557896364E074-1991
chr85789651257896552E074-1803
chr85789665857896727E074-1628
chr85789679857896842E074-1513
chr85789692257896997E074-1358
chr85789726157897368E074-987
chr85789745557897505E074-850
chr85789810457898148E074-207
chr85789816657898216E074-139
chr85789850157898545E074146
chr85789858057898640E074225
chr85789928357899333E074928
chr85789943057899470E0741075
chr85789948457899528E0741129
chr85790010657900233E0741751
chr85790086657901022E0742511
chr85790105157901116E0742696
chr85790117557901340E0742820
chr85790212157902220E0743766
chr85790230457902354E0743949
chr85790257157902611E0744216
chr85790274357902783E0744388
chr85790294657903011E0744591
chr85790340457903444E0745049
chr85790734957907409E0748994
chr85790743457907623E0749079
chr85792251957922657E07424164
chr85792287657923560E07424521
chr85792685157926920E07428496
chr85792699057927496E07428635
chr85794250657943071E07444151
chr85794322657943517E07444871
chr85794369257943776E07445337
chr85790340457903444E0815049
chr85791841957918475E08120064
chr85791908357920078E08120728
chr85792251957922657E08124164
chr85792287657923560E08124521
chr85792685157926920E08128496
chr85792699057927496E08128635
chr85792760657927656E08129251
chr85792799857928165E08129643
chr85792818657928269E08129831
chr85790340457903444E0825049
chr85791841957918475E08220064
chr85792287657923560E08224521
chr85792799857928165E08229643










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr85790505357907285E0676698
chr85790505357907285E0686698
chr85790505357907285E0696698
chr85790505357907285E0706698
chr85790505357907285E0716698
chr85790505357907285E0726698
chr85790505357907285E0736698
chr85790505357907285E0746698
chr85790505357907285E0816698
chr85790505357907285E0826698