rs368028

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0180 (5406/29944,GnomAD)
C==0141 (4123/29118,TOPMED)
C==0272 (1362/5008,1000G)
C==0158 (608/3854,ALSPAC)
C==0152 (562/3708,TWINSUK)
chr6:169411199 (GRCh38.p7) (6q27)
AD
GWASdb2
1   publication(s)
See rs on genome
18 Enhancers around
2 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.169411199C>T
GRCh37.p13 chr 6NC_000006.11:g.169811294C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.089T=0.911
1000GenomesAmericanSub694C=0.310T=0.690
1000GenomesEast AsianSub1008C=0.592T=0.408
1000GenomesEuropeSub1006C=0.160T=0.840
1000GenomesGlobalStudy-wide5008C=0.272T=0.728
1000GenomesSouth AsianSub978C=0.280T=0.720
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.158T=0.842
The Genome Aggregation DatabaseAfricanSub8718C=0.104T=0.896
The Genome Aggregation DatabaseAmericanSub838C=0.340T=0.660
The Genome Aggregation DatabaseEast AsianSub1614C=0.615T=0.385
The Genome Aggregation DatabaseEuropeSub18474C=0.172T=0.827
The Genome Aggregation DatabaseGlobalStudy-wide29944C=0.180T=0.819
The Genome Aggregation DatabaseOtherSub300C=0.160T=0.840
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.141T=0.858
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.152T=0.848
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs3680280.000911alcohol dependence21314694

eQTL of rs368028 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr6:169811294RP1-137D17.1ENSG00000226194.1C>T1.3823e-422814Cerebellar_Hemisphere
Chr6:169811294RP1-137D17.1ENSG00000226194.1C>T9.3356e-422814Caudate_basal_ganglia

meQTL of rs368028 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6169762720169763070E068-48224
chr6169765748169766004E069-45290
chr6169766117169766167E069-45127
chr6169827198169828587E07015904
chr6169828658169829133E07017364
chr6169850221169850528E07038927
chr6169850536169850627E07039242
chr6169850767169850891E07039473
chr6169850221169850528E07138927
chr6169850536169850627E07139242
chr6169850767169850891E07139473
chr6169765748169766004E072-45290
chr6169766117169766167E072-45127
chr6169766241169766338E072-44956
chr6169766388169766448E072-44846
chr6169777940169778203E082-33091
chr6169778760169778855E082-32439
chr6169828658169829133E08217364






Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr6169852002169852614E06740708
chr6169852002169852614E07140708