rs3807235

Homo sapiens
A>C
DPP6 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0155 (4673/29974,GnomAD)
A==0162 (4719/29118,TOPMED)
A==0143 (715/5008,1000G)
A==0117 (450/3854,ALSPAC)
A==0124 (461/3708,TWINSUK)
chr7:154685668 (GRCh38.p7) (7q36.2)
AD
GWASdb2
1   publication(s)
See rs on genome
59 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.154685668A>C
GRCh37.p13 chr 7NC_000007.13:g.154477378A>C
DPP6 RefSeqGeneNG_033878.1:g.803335A>C

Gene: DPP6, dipeptidyl peptidase like 6(plus strand)

Molecule type Change Amino acid[Codon] SO Term
DPP6 transcript variant 3NM_001039350.2:c.N/AIntron Variant
DPP6 transcript variant 4NM_001290252.1:c.N/AIntron Variant
DPP6 transcript variant 2NM_001936.4:c.N/AIntron Variant
DPP6 transcript variant 1NM_130797.3:c.N/AIntron Variant
DPP6 transcript variant 5NM_001290253.1:c.N/AGenic Downstream Transcript Variant
DPP6 transcript variant X1XM_017011808.1:c.N/AIntron Variant
DPP6 transcript variant X2XM_017011809.1:c.N/AIntron Variant
DPP6 transcript variant X3XM_017011810.1:c.N/AIntron Variant
DPP6 transcript variant X4XM_017011811.1:c.N/AIntron Variant
DPP6 transcript variant X5XM_017011812.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.238C=0.762
1000GenomesAmericanSub694A=0.180C=0.820
1000GenomesEast AsianSub1008A=0.081C=0.919
1000GenomesEuropeSub1006A=0.115C=0.885
1000GenomesGlobalStudy-wide5008A=0.143C=0.857
1000GenomesSouth AsianSub978A=0.080C=0.920
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.117C=0.883
The Genome Aggregation DatabaseAfricanSub8716A=0.225C=0.775
The Genome Aggregation DatabaseAmericanSub838A=0.160C=0.840
The Genome Aggregation DatabaseEast AsianSub1620A=0.095C=0.905
The Genome Aggregation DatabaseEuropeSub18498A=0.128C=0.871
The Genome Aggregation DatabaseGlobalStudy-wide29974A=0.155C=0.844
The Genome Aggregation DatabaseOtherSub302A=0.140C=0.860
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.162C=0.837
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.124C=0.876
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs38072350.000925alcohol consumption (maxi-drinks)24277619

eQTL of rs3807235 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs3807235 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7154471378154471698E067-5680
chr7154476794154476943E067-435
chr7154461986154462425E068-14953
chr7154465968154466027E068-11351
chr7154466073154466123E068-11255
chr7154466173154466223E068-11155
chr7154476794154476943E068-435
chr7154490506154490737E06813128
chr7154490747154490853E06813369
chr7154491107154491148E06813729
chr7154491210154491506E06813832
chr7154476794154476943E069-435
chr7154477007154477154E069-224
chr7154490506154490737E06913128
chr7154490747154490853E06913369
chr7154491107154491148E06913729
chr7154491210154491506E06913832
chr7154525640154525690E06948262
chr7154476052154476166E070-1212
chr7154476794154476943E070-435
chr7154477007154477154E070-224
chr7154477205154477269E070-109
chr7154477425154477506E07047
chr7154478160154478200E070782
chr7154478282154478362E070904
chr7154479773154479823E0702395
chr7154485029154485099E0707651
chr7154485132154485313E0707754
chr7154485527154485754E0708149
chr7154430097154430199E071-47179
chr7154432119154432169E071-45209
chr7154476794154476943E071-435
chr7154477007154477154E071-224
chr7154477205154477269E071-109
chr7154477425154477506E07147
chr7154464480154464699E072-12679
chr7154464911154465023E072-12355
chr7154465075154465131E072-12247
chr7154476794154476943E072-435
chr7154477007154477154E072-224
chr7154477205154477269E072-109
chr7154476794154476943E074-435
chr7154490506154490737E07413128
chr7154490747154490853E07413369
chr7154476794154476943E081-435
chr7154477007154477154E081-224
chr7154485029154485099E0817651
chr7154485132154485313E0817754
chr7154485527154485754E0818149
chr7154485929154485969E0818551
chr7154486554154486634E0819176
chr7154486784154486834E0819406
chr7154476794154476943E082-435
chr7154484846154484962E0827468
chr7154485029154485099E0827651
chr7154485132154485313E0827754
chr7154485527154485754E0828149
chr7154485929154485969E0828551
chr7154511736154511949E08234358