rs3856372

Homo sapiens
T>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0403 (12063/29934,GnomAD)
A=0360 (10488/29118,TOPMED)
A=0428 (2142/5008,1000G)
A=0454 (1751/3854,ALSPAC)
A=0470 (1742/3708,TWINSUK)
chr2:129239510 (GRCh38.p7) (2q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
16 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.129239510T>A
GRCh37.p13 chr 2NC_000002.11:g.129997083T>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.817A=0.183
1000GenomesAmericanSub694T=0.480A=0.520
1000GenomesEast AsianSub1008T=0.293A=0.707
1000GenomesEuropeSub1006T=0.568A=0.432
1000GenomesGlobalStudy-wide5008T=0.572A=0.428
1000GenomesSouth AsianSub978T=0.600A=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.546A=0.454
The Genome Aggregation DatabaseAfricanSub8710T=0.772A=0.228
The Genome Aggregation DatabaseAmericanSub838T=0.470A=0.530
The Genome Aggregation DatabaseEast AsianSub1620T=0.223A=0.777
The Genome Aggregation DatabaseEuropeSub18466T=0.552A=0.447
The Genome Aggregation DatabaseGlobalStudy-wide29934T=0.597A=0.403
The Genome Aggregation DatabaseOtherSub300T=0.620A=0.380
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.639A=0.360
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.530A=0.470
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs38563726.04E-06alcohol dependence (age at onset)24962325

eQTL of rs3856372 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs3856372 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2129990903129991022E070-6061
chr2129991443129991904E070-5179
chr2129990903129991022E081-6061
chr2129991443129991904E081-5179
chr2129996773129997036E081-47
chr2130010223130010353E08113140
chr2130010398130011293E08113315
chr2130038915130039052E08141832
chr2130039472130039687E08142389
chr2130039843130039996E08142760
chr2129996773129997036E082-47
chr2130010223130010353E08213140
chr2130038591130038845E08241508
chr2130038915130039052E08241832
chr2130039472130039687E08242389
chr2130039843130039996E08242760