rs3857282

Homo sapiens
G>C
ARL15 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0370 (11067/29858,GnomAD)
G==0397 (11585/29118,TOPMED)
G==0456 (2283/5008,1000G)
G==0314 (1212/3854,ALSPAC)
G==0311 (1153/3708,TWINSUK)
chr5:54248075 (GRCh38.p7) (5q11.2)
AD
GWASdb2
1   publication(s)
See rs on genome
23 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.54248075G>C
GRCh37.p13 chr 5NC_000005.9:g.53543905G>C

Gene: ARL15, ADP ribosylation factor like GTPase 15(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ARL15 transcriptNM_019087.2:c.N/AIntron Variant
ARL15 transcript variant X1XM_011543498.2:c.N/AIntron Variant
ARL15 transcript variant X2XM_011543499.2:c.N/AIntron Variant
ARL15 transcript variant X3XM_011543500.2:c.N/AIntron Variant
ARL15 transcript variant X4XM_017009598.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.510C=0.490
1000GenomesAmericanSub694G=0.540C=0.460
1000GenomesEast AsianSub1008G=0.571C=0.429
1000GenomesEuropeSub1006G=0.310C=0.690
1000GenomesGlobalStudy-wide5008G=0.456C=0.544
1000GenomesSouth AsianSub978G=0.350C=0.650
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.314C=0.686
The Genome Aggregation DatabaseAfricanSub8670G=0.468C=0.532
The Genome Aggregation DatabaseAmericanSub834G=0.520C=0.480
The Genome Aggregation DatabaseEast AsianSub1602G=0.604C=0.396
The Genome Aggregation DatabaseEuropeSub18452G=0.300C=0.699
The Genome Aggregation DatabaseGlobalStudy-wide29858G=0.370C=0.629
The Genome Aggregation DatabaseOtherSub300G=0.240C=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.397C=0.602
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.311C=0.689
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs38572822.6E-06alcohol dependence (age at onset)24962325

eQTL of rs3857282 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs3857282 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr55359219153592302E06748286
chr55359230553592489E06748400
chr55352492153525456E068-18449
chr55359156353591979E06847658
chr55359219153592302E06848286
chr55359230553592489E06848400
chr55357394153574185E06930036
chr55357422253574433E06930317
chr55351066653510874E070-33031
chr55351115053511650E070-32255
chr55351327153513323E070-30582
chr55357394153574185E07230036
chr55357422253574433E07230317
chr55357444553574505E07230540
chr55357422253574433E07430317
chr55357444553574505E07430540
chr55359119253591246E07447287
chr55359156353591979E07447658
chr55359219153592302E07448286
chr55359230553592489E07448400
chr55351066653510874E081-33031
chr55351115053511650E081-32255
chr55351115053511650E082-32255








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr55355060653550896E0716701