rs3862445

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0369 (11072/29956,GnomAD)
T==0440 (12839/29118,TOPMED)
T==0362 (1813/5008,1000G)
T==0260 (1003/3854,ALSPAC)
T==0252 (935/3708,TWINSUK)
chr16:7792520 (GRCh38.p7) (16p13.3)
AD
GWASdb2
1   publication(s)
See rs on genome
27 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.7792520T>C
GRCh37.p13 chr 16NC_000016.9:g.7842522T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.767C=0.233
1000GenomesAmericanSub694T=0.220C=0.780
1000GenomesEast AsianSub1008T=0.164C=0.836
1000GenomesEuropeSub1006T=0.225C=0.775
1000GenomesGlobalStudy-wide5008T=0.362C=0.638
1000GenomesSouth AsianSub978T=0.260C=0.740
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.260C=0.740
The Genome Aggregation DatabaseAfricanSub8722T=0.702C=0.298
The Genome Aggregation DatabaseAmericanSub838T=0.180C=0.820
The Genome Aggregation DatabaseEast AsianSub1616T=0.175C=0.825
The Genome Aggregation DatabaseEuropeSub18478T=0.240C=0.759
The Genome Aggregation DatabaseGlobalStudy-wide29956T=0.369C=0.630
The Genome Aggregation DatabaseOtherSub302T=0.220C=0.780
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.440C=0.559
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.252C=0.748
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs38624450.00038alcohol dependence20201924

eQTL of rs3862445 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs3862445 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1677945607795609E067-46913
chr1677959737796042E067-46480
chr1677945607795609E068-46913
chr1677959737796042E068-46480
chr1677945607795609E069-46913
chr1677959737796042E069-46480
chr1677945607795609E070-46913
chr1677959737796042E070-46480
chr1677965277796665E070-45857
chr1677966967796782E070-45740
chr1677969387797313E070-45209
chr1678056867805786E070-36736
chr1677945607795609E071-46913
chr1677945607795609E072-46913
chr1677942627794314E073-48208
chr1677945607795609E073-46913
chr1677959737796042E073-46480
chr1677945607795609E074-46913
chr1677945607795609E081-46913
chr1677959737796042E081-46480
chr1677965277796665E081-45857
chr1677966967796782E081-45740
chr1677969387797313E081-45209
chr1678365367836658E081-5864
chr1678369237837101E081-5421
chr1677945607795609E082-46913
chr1677969387797313E082-45209