rs3905310

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0099 (2967/29936,GnomAD)
A=0091 (2662/29118,TOPMED)
A=0225 (1126/5008,1000G)
A=0053 (204/3854,ALSPAC)
A=0041 (151/3708,TWINSUK)
chr6:47351082 (GRCh38.p7) (6p12.3)
AD
GWASdb2
2   publication(s)
See rs on genome
12 Enhancers around
37 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.47351082G>A
GRCh37.p13 chr 6NC_000006.11:g.47318818G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.890A=0.110
1000GenomesAmericanSub694G=0.700A=0.300
1000GenomesEast AsianSub1008G=0.405A=0.595
1000GenomesEuropeSub1006G=0.967A=0.033
1000GenomesGlobalStudy-wide5008G=0.775A=0.225
1000GenomesSouth AsianSub978G=0.860A=0.140
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.947A=0.053
The Genome Aggregation DatabaseAfricanSub8714G=0.906A=0.094
The Genome Aggregation DatabaseAmericanSub838G=0.680A=0.320
The Genome Aggregation DatabaseEast AsianSub1600G=0.404A=0.596
The Genome Aggregation DatabaseEuropeSub18482G=0.951A=0.049
The Genome Aggregation DatabaseGlobalStudy-wide29936G=0.900A=0.099
The Genome Aggregation DatabaseOtherSub302G=0.930A=0.070
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.908A=0.091
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.959A=0.041
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res
22628180Genome-wide association uncovers shared genetic effects among personality traits and mood states.Luciano MAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs39053104.96E-05alcohol dependence21314694

eQTL of rs3905310 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs3905310 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr64727113347271419E070-47399
chr64727150047271615E070-47203
chr64727174147271799E070-47019
chr64727340547273455E073-45363
chr64727021147270317E081-48501
chr64727340547273455E081-45363
chr64727384647273899E081-44919
chr64727403447274109E081-44709
chr64727472847274853E081-43965
chr64736419747364408E08245379
chr64736461947364699E08245801
chr64736485247364925E08246034




Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr64727570447275933E067-42885
chr64727596447276250E067-42568
chr64727627447276341E067-42477
chr64727634347278084E067-40734
chr64727570447275933E068-42885
chr64727596447276250E068-42568
chr64727627447276341E068-42477
chr64727634347278084E068-40734
chr64727570447275933E069-42885
chr64727596447276250E069-42568
chr64727627447276341E069-42477
chr64727634347278084E069-40734
chr64727627447276341E070-42477
chr64727634347278084E070-40734
chr64727570447275933E071-42885
chr64727596447276250E071-42568
chr64727627447276341E071-42477
chr64727634347278084E071-40734
chr64727570447275933E072-42885
chr64727596447276250E072-42568
chr64727627447276341E072-42477
chr64727634347278084E072-40734
chr64727570447275933E073-42885
chr64727596447276250E073-42568
chr64727627447276341E073-42477
chr64727634347278084E073-40734
chr64727570447275933E074-42885
chr64727596447276250E074-42568
chr64727627447276341E074-42477
chr64727634347278084E074-40734
chr64727570447275933E081-42885
chr64727627447276341E081-42477
chr64727634347278084E081-40734
chr64727570447275933E082-42885
chr64727596447276250E082-42568
chr64727627447276341E082-42477
chr64727634347278084E082-40734