rs3908110

Homo sapiens
C>A / C>T
None
Check p-value
SNV (Single Nucleotide Variation)
A=0322 (9626/29886,GnomAD)
A=0368 (1843/5008,1000G)
chr2:4369251 (GRCh38.p7) (2p25.3)
AD
GWASdb2
1   publication(s)
See rs on genome
90 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.4369251C>A
GRCh38.p7 chr 2NC_000002.12:g.4369251C>T
GRCh37.p13 chr 2NC_000002.11:g.4416841C>A
GRCh37.p13 chr 2NC_000002.11:g.4416841C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.331A=0.666
1000GenomesAmericanSub694C=0.800A=0.19,
1000GenomesEast AsianSub1008C=0.772A=0.228
1000GenomesEuropeSub1006C=0.760A=0.228
1000GenomesGlobalStudy-wide5008C=0.625A=0.368
1000GenomesSouth AsianSub978C=0.610A=0.38,
The Genome Aggregation DatabaseAfricanSub8708C=0.386T=0.003
The Genome Aggregation DatabaseAmericanSub836C=0.800T=0.01,
The Genome Aggregation DatabaseEast AsianSub1612C=0.780T=0.001
The Genome Aggregation DatabaseEuropeSub18430C=0.781T=0.016
The Genome Aggregation DatabaseGlobalStudy-wide29886C=0.666T=0.011
The Genome Aggregation DatabaseOtherSub300C=0.780T=0.01,
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs39081100.000187alcohol consumption (maxi-drinks)24277619

eQTL of rs3908110 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs3908110 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr22838652228386799E067-25172
chr22838684528387852E067-24119
chr22844738828447892E06735417
chr22844789528448189E06735924
chr22844819528448276E06736224
chr22844828628448372E06736315
chr22845404828454568E06742077
chr22845501128455068E06743040
chr22845510028455874E06743129
chr22845597728456677E06744006
chr22837125328371352E068-40619
chr22837302128373124E068-38847
chr22838652228386799E068-25172
chr22838684528387852E068-24119
chr22838803028388375E068-23596
chr22839499928395172E068-16799
chr22844738828447892E06835417
chr22844789528448189E06835924
chr22844819528448276E06836224
chr22844828628448372E06836315
chr22844840928448690E06836438
chr22845404828454568E06842077
chr22845501128455068E06843040
chr22845510028455874E06843129
chr22845597728456677E06844006
chr22846120128461633E06849230
chr22838652228386799E069-25172
chr22838684528387852E069-24119
chr22844789528448189E06935924
chr22844819528448276E06936224
chr22844828628448372E06936315
chr22844840928448690E06936438
chr22845404828454568E06942077
chr22845501128455068E06943040
chr22845510028455874E06943129
chr22838652228386799E070-25172
chr22838684528387852E070-24119
chr22838803028388375E070-23596
chr22842978528429951E07017814
chr22843934628439458E07027375
chr22838652228386799E071-25172
chr22838684528387852E071-24119
chr22842978528429951E07117814
chr22844738828447892E07135417
chr22844789528448189E07135924
chr22844819528448276E07136224
chr22845404828454568E07142077
chr22845501128455068E07143040
chr22845510028455874E07143129
chr22845597728456677E07144006
chr22846076828460856E07148797
chr22846120128461633E07149230
chr22838652228386799E072-25172
chr22838684528387852E072-24119
chr22843934628439458E07227375
chr22844728328447383E07235312
chr22844738828447892E07235417
chr22844789528448189E07235924
chr22844819528448276E07236224
chr22844828628448372E07236315
chr22845404828454568E07242077
chr22845501128455068E07243040
chr22845510028455874E07243129
chr22845597728456677E07244006
chr22846120128461633E07249230
chr22843934628439458E07327375
chr22844789528448189E07335924
chr22844819528448276E07336224
chr22844828628448372E07336315
chr22845510028455874E07343129
chr22845597728456677E07344006
chr22846120128461633E07349230
chr22838652228386799E074-25172
chr22838684528387852E074-24119
chr22838803028388375E074-23596
chr22844789528448189E07435924
chr22844819528448276E07436224
chr22844828628448372E07436315
chr22844840928448690E07436438
chr22845510028455874E07443129
chr22845597728456677E07444006
chr22846076828460856E07448797
chr22846120128461633E07449230
chr22838539128385849E081-26122
chr22838607728386169E081-25802
chr22838652228386799E081-25172
chr22838684528387852E081-24119
chr22838803028388375E081-23596
chr22841665728416814E0824686
chr22841698428417329E0825013